Evidence map›Paper›PMID 9788905›Full record

ReviewEnvironmental health perspectives1998

Oxidative stress and antioxidants at biosurfaces: plants, skin, and respiratory tract surfaces.

C E Cross, A van der Vliet, S Louie, J J Thiele, B Halliwell

Abstract readReview
In one paragraph

Review in Environmental health perspectives, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Reflections of an aging free radical.Free radical biology & medicine · 2020
    Review
  6. Article
  7. Article
  8. Circulating oxidative stress caused byJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Acidity enhances the formation of a persistent ozonide at aqueous ascorbate/ozone gas interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C E CrossCenter for Comparative Lung Biology and Medicine, University of California, Davis, USA. cecross@ucdavis.edu
A van der Vliet
S Louie
J J Thiele
B Halliwell

Funding

OXIDANT AIR POLLUTANT EFFECTS ON LUNG LINING FLUID(S)R01HL047628 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI CROSS, CARROLL E · 1992 to 2000
$167k
NITRIC OXIDE-MEDIATED PROTEIN MODIFICATION IN THE LUNGR01HL057452 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI CROSS, CARROLL E · 1997 to 1999
–
NHLBI NIH HHS HL 47628NHLBI NIH HHS HL 57452
6 · The paper itself

Abstract

Atmospheric pollutants represent an important source of oxidative and nitrosative stress to both terrestrial plants and to animals. The exposed biosurfaces of plants and animals are directly exposed to these pollutant stresses. Not surprisingly, living organisms have developed complex integrated extracellular and intracellular defense systems against stresses related to reactive oxygen and nitrogen species (ROS, RNS), including O3 and NO2. Plant and animal epithelial surfaces and respiratory tract surfaces contain antioxidants that would be expected to provide defense against environmental stress caused by ambient ROS and RNS, thus ameliorating their injurious effects on more delicate underlying cellular constituents. Parallelisms among these surfaces with regard to their antioxidant constituents and environmental oxidants are presented. The reactive substances at these biosurfaces not only represent an important protective system against oxidizing environments, but products of their reactions with ROS/RNS may also serve as biomarkers of environmental oxidative stress. Moreover, the reaction products may also induce injury to underlying cells or cause cell activation, resulting in production of proinflammatory substances including cytokines. In this review we discuss antioxidant defense systems against environmental toxins in plant cell wall/apoplastic fluids, dead keratinized cells/interstitial fluids of stratum corneum (the outermost skin layer), and mucus/respiratory tract lining fluids.

Indexed as

Oxidative StressAir PollutantsAnimalsAntioxidantsBody FluidsNitrogenPlantsReactive Oxygen SpeciesRespiratory SystemSkinAir PollutantsAntioxidantsNitrogenReactive Oxygen Species

Identifiers

PMID9788905
PMCPMC1533356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.