ArticleInfection and immunity1998
Diversity in protein synthesis and viability of Helicobacter pylori coccoid forms in response to various stimuli.
Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 71 citations in OpenAlex.
- CoccoidVirulence · 2025Review
- Review
- Myricetin as an Antivirulence Compound Interfering with a Morphological Transformation into Coccoid Forms and Potentiating Activity of Antibiotics againstInternational journal of molecular sciences · 2021Article
- Transformation ofPathogens (Basel, Switzerland) · 2020Review
- High expression of Helicobacter pylori VapD in both the intracellular environment and biopsies from gastric patients with severity.PloS one · 2020Article
- Significance of dormant forms ofWorld journal of gastroenterology · 2017Review
- Understanding the dimorphic lifestyles of human gastric pathogen Helicobacter pylori using the SWATH-based proteomics approach.Scientific reports · 2016Article
- Assessment of cagE and babA mRNA expression during morphological conversion of Helicobacter pylori from spiral to coccoid.Current microbiology · 2013Article
- Stimulation of growth of the human gastric pathogen Helicobacter pylori by atmospheric level of oxygen under high carbon dioxide tension.BMC microbiology · 2011Article
- Characteristics and interactions of Helicobacter pylori and H. pylori-infected human gastroduodenal epithelium in peptic ulcer: a transmission electron microscopy study.Digestive diseases and sciences · 2010Article
- The changes of proteomes components of Helicobacter pylori in response to acid stress without urea.Journal of microbiology (Seoul, Korea) · 2008Article
- Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape.PLoS pathogens · 2006Article
- Cloning and sequencing of cagA gene fragment of Helicobacter pylori with coccoid form.World journal of gastroenterology · 2004Article
- Helicobacter pylori expresses an autolytic enzyme: gene identification, cloning, and theoretical protein structure.Journal of bacteriology · 2002Article
- Immunoglobulin G antibody response to infection with coccoid forms of Helicobacter pylori.Clinical and diagnostic laboratory immunology · 2002Article
- Effect of cold starvation, acid stress, and nutrients on metabolic activity of Helicobacter pylori.Applied and environmental microbiology · 2002Article
- Virulence and potential pathogenicity of coccoid Helicobacter pylori induced by antibiotics.World journal of gastroenterology · 2001Article
- Competition of various beta-lactam antibiotics for the major penicillin-binding proteins of Helicobacter pylori: antibacterial activity and effects on bacterial morphology.Antimicrobial agents and chemotherapy · 1999Article
- The morphological transition of Helicobacter pylori cells from spiral to coccoid is preceded by a substantial modification of the cell wall.Journal of bacteriology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The viability of the coccoid forms of Helicobacter pylori was evaluated by assessing protein synthesis. Metabolic labeling studies showed the synthesis of proteins and the specific protein profiles of H. pylori coccoids produced under various conditions. Harsh conditions such as aerobiosis and starvation (lack of horse serum) in the culture did not affect the synthesis of proteins in the coccoids. Lowering of the pH to that of gastric secretions induced expression of several proteins in the coccoids. However, the coccoids produced under prolonged microaerobic conditions exhibited a profile of acid stress-induced protein expression different from that induced by aerobiosis or starvation. Our data suggest that coccoid H. pylori exhibits diversity in viability following exposure to different stresses and that the response to acid stress of coccoid H. pylori could be involved in infection of the host stomach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.