ArticleProceedings of the National Academy of Sciences of the United States of America1998
Cloning of inversion breakpoints in the Anopheles gambiae complex traces a transposable element at the inversion junction.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Chromosomal inversions modulate 3D chromatin interactions and regulatory architecture inResearch square · 2026Article
- Transposable element variants and their potential adaptive impact in urban populations of the malaria vectorGenome research · 2022Article
- Review
- Widespread Impact of Chromosomal Inversions on Gene Expression Uncovers Robustness via Phenotypic Buffering.Molecular biology and evolution · 2016Article
- Genomic composition and evolution of Aedes aegypti chromosomes revealed by the analysis of physically mapped supercontigs.BMC biology · 2014Article
- Adaptation through chromosomal inversions in Anopheles.Frontiers in genetics · 2014Review
- Article
- A new chromosomal phylogeny supports the repeated origin of vectorial capacity in malaria mosquitoes of the Anopheles gambiae complex.PLoS pathogens · 2012Article
- Reading TE leaves: new approaches to the identification of transposable element insertions.Genome research · 2011Article
- Breakpoint structure of the Anopheles gambiae 2Rb chromosomal inversion.Malaria journal · 2010Article
- Article
- The transposon Galileo generates natural chromosomal inversions in Drosophila by ectopic recombination.PloS one · 2009Article
- Cloning and sequencing of the breakpoint regions of inversion 5g fixed in Drosophila buzzatii.Chromosoma · 2009Article
- Article
- Revisiting the Impact of Inversions in Evolution: From Population Genetic Markers to Drivers of Adaptive Shifts and Speciation?Annual review of ecology, evolution, and systematics · 2008Article
- Chromosomal plasticity and evolutionary potential in the malaria vector Anopheles gambiae sensu stricto: insights from three decades of rare paracentric inversions.BMC evolutionary biology · 2008Article
- Distribution of the transposable elements bilbo and gypsy in original and colonizing populations of Drosophila subobscura.BMC evolutionary biology · 2008Article
- Article
- Segmental duplication implicated in the genesis of inversion 2Rj of Anopheles gambiae.PloS one · 2007Article
- Principles of genome evolution in the Drosophila melanogaster species group.PLoS biology · 2007Article
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5 authors.
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Abstract
Anopheles arabiensis, one of the two most potent malaria vectors of the gambiae complex, is characterized by the presence of chromosomal paracentric inversions. Elucidation of the nature and the dynamics of these inversions is of paramount importance for the understanding of the population genetics and evolutionary biology of this mosquito and of the impact on malaria epidemiology. We report here the cloning of the breakpoints of the naturally occurring polymorphic inversion 2Rd' of A. arabiensis. A cDNA clone that cytologically mapped on the proximal breakpoint was the starting material for the isolation of a cosmid clone that spanned the breakpoint. Analysis of the surrounding sequences demonstrated that adjacent to the distal breakpoint lies a repetitive element that exhibits distinct distribution in different A. arabiensis strains. Sequencing analysis of that area revealed elements characteristic of transposable element terminal repeats. We called this presumed transposable element Odysseus. The presence of Odysseus at the junction of the naturally occuring inversion 2Rd' suggests that the inversion may be the result of the transposable element's activity. Characteristics of Odysseus' terminal region as well as its cytological distribution in different strains may indicate a relatively recent activity of Odysseus.
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