Evidence map›Paper›PMID 9768580›Full record

ArticleThe Journal of allergy and clinical immunology1998

Sinusitis in the common cold.

T Puhakka, M J Mäkelä, A Alanen, T Kallio, L Korsoff, P Arstila, M Leinonen, M Pulkkinen, J Suonpää, J Mertsola and 1 more

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Annual trends in Google searches provides insights related to rhinosinusitis exacerbations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  4. Article
  5. Inflammatory Biomarkers During Bacterial Acute Rhinosinusitis.Current allergy and asthma reports · 2018
    Review
  6. Review
  7. Article
  8. The Korean Cough Guideline: Recommendation and Summary Statement.Tuberculosis and respiratory diseases · 2016
    Review
  9. Chronic rhinosinusitis in children.International journal of pediatrics · 2012
    Article
  10. Acute sinusitis.Canadian family physician Medecin de famille canadien · 2011
    Article
  11. Review
  12. Upper respiratory tract infections (including otitis media).Pediatric clinics of North America · 2009
    Review
  13. Upper respiratory tract infections in athletes.Clinics in sports medicine · 2007
    Review
  14. Review
  15. Drug management in chronic rhinosinusitis: identification of the needs.Therapeutics and clinical risk management · 2007
    Article
  16. Bacterial coinfections in children with viral wheezing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2006
    Article
  17. Review
  18. Article
  19. Viral infections and susceptibility to recurrent sinusitis.Current allergy and asthma reports · 2005
    Review
  20. Rhinosinusitis: establishing definitions for clinical research and patient care.The Journal of allergy and clinical immunology · 2004
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

T PuhakkaDepartment of Pediatrics, Turku University Hospital, Finland.
M J Mäkelä
A Alanen
T Kallio
L Korsoff
P Arstila
M Leinonen
M Pulkkinen
J Suonpää
J Mertsola
O Ruuskanen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute community-acquired sinusitis is considered a bacterial complication of the common cold. Radiologic abnormalities in sinuses occur, however, in most patients with upper respiratory virus infections.

objectiveAssessment of the occurrence, clinical profile, laboratory findings, and outcome of radiologically confirmed sinusitis was carried out as part of a common cold study in young adults.

methodsClinical examinations and radiography of the paranasal sinuses were carried out on days 1, 7, and 21 in 197 patients with the common cold. The symptoms were recorded on diary cards on days 1 to 20. Ten viruses and 5 bacteria were studied as etiologic agents of common cold as reported earlier. Serum C reactive protein concentrations, erythrocyte sedimentation rates, and total white blood cell counts with differentials were determined in 40 randomized subjects on day 7. The effect of 6 days of intranasal fluticasone propionate treatment of the common cold in the prevention of sinusitis was analyzed.

resultsOn day 7, 39% of patients with the common cold in the placebo group (n = 98) had sinusitis, which we would prefer to call viral sinusitis. The symptoms of patients with sinusitis and those without it were not clinically distinguishable. Viral infection was detected in 81.6% of patients with sinusitis. No significantly increased levels of antibodies to bacteria were detected. Serum C reactive protein concentrations, erythrocyte sedimentation rates, and white blood cell counts were low in patients with sinusitis. All patients made a clinical recovery within 21 days without antibiotic treatment. Fluticasone propionate treatment tended to prevent paranasal sinusitis, especially in rhinovirus-positive subjects.

conclusionViral sinusitis frequently occurs in the early days of the common cold, but it is a self-limited illness. The sinuses should not be imaged in patients with the common cold if the signs and symptoms of illness gradually become less severe and no specific signs suggestive of bacterial sinusitis occur.

Indexed as

AdultAndrostadienesAnti-Allergic AgentsAnti-Inflammatory AgentsBlood SedimentationCommon ColdCommunity-Acquired InfectionsC-Reactive ProteinFemaleFluticasoneHumansLeukocyte CountMaleParanasal SinusesRadiographySinusitisAndrostadienesAnti-Allergic AgentsAnti-Inflammatory AgentsC-Reactive ProteinFluticasone

Identifiers

PMID9768580
PMCPMC7112288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.