ArticleJournal of virology1998
Attachment and growth of human rotaviruses RV-3 and S12/85 in Caco-2 cells depend on VP4.
Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Human Rotaviruses of Multiple Genotypes Acquire Conserved VP4 Mutations during Serial Passage.Viruses · 2024Article
- Vaccine evaluation and genotype characterization in children infected with rotavirus in Qatar.Pediatric research · 2023Article
- Genetic Diversity of Human Rotavirus A Among Hospitalized Children Under-5 Years in Lebanon.Frontiers in immunology · 2020Article
- 25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes.Redox biology · 2018Article
- A universal mammalian vaccine cell line substrate.PloS one · 2017Article
- Modeling of the rotavirus group C capsid predicts a surface topology distinct from other rotavirus species.Virology · 2016Article
- Identification of Equine Lactadherin-derived Peptides That Inhibit Rotavirus Infection via Integrin Receptor Competition.The Journal of biological chemistry · 2015Article
- Relative roles of GM1 ganglioside, N-acylneuraminic acids, and α2β1 integrin in mediating rotavirus infection.Journal of virology · 2014Article
- Determinants of the specificity of rotavirus interactions with the alpha2beta1 integrin.The Journal of biological chemistry · 2011Article
- Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences.Journal of virology · 2004Article
- Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry.Journal of virology · 2003Article
- Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit.Journal of virology · 2003Article
- Interactions of rotavirus VP4 spike protein with the endosomal protein Rab5 and the prenylated Rab acceptor PRA1.Journal of virology · 2003Article
- Growth of rotaviruses in primary pancreatic cells.Journal of virology · 2002Article
- Trypsin cleavage stabilizes the rotavirus VP4 spike.Journal of virology · 2001Article
- Primary murine small intestinal epithelial cells, maintained in long-term culture, are susceptible to rotavirus infection.Journal of virology · 2000Article
- Rotavirus spike protein VP4 is present at the plasma membrane and is associated with microtubules in infected cells.Journal of virology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies with human neonatal rotaviruses RV-3 and S12/85 and their reassortants showed that VP4 is a determinant of rotavirus attachment to and growth in Caco-2 cells. The binding of these viruses to MA104 and Caco-2 cells correlated with their growth ability. Virus sensitivity to trypsin and the VP4 fusion region may be implicated in these processes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.