Transmission disequilibrium, family controls, and great expectations.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Molecular genetics of obsessive-compulsive disorder: a comprehensive meta-analysis of genetic association studies.Molecular psychiatry · 2013
   Pooled it
2. Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity.BMC medical genetics · 2006
   Pooled it
3. Germline genetic profiling in prostate cancer: latest developments and potential clinical applications.Future science OA · 2016
   Review
4. The genetic epidemiology of prostate cancer and its clinical implications.Nature reviews. Urology · 2014
   Review
5. Comprehensive analysis of polymorphisms throughout GAD1 gene: a family-based association study in schizophrenia.Journal of neural transmission (Vienna, Austria : 1996) · 2008
   Article
6. Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.Proceedings of the National Academy of Sciences of the United States of America · 2007
   Article
7. Family-based association study of Epsin 4 and Schizophrenia.Molecular psychiatry · 2006
   Article
8. Linkage analysis of five candidate genes and essential hypertension in 106 Chinese nuclear families.Journal of human hypertension · 2003
   Article
9. CD40L association with protection from severe malaria.Genes and immunity · 2002
   Article
10. Role of genetics in osteoporosis.Endocrine · 2002
    Review
11. Gene-environment interactions--the BioBank UK study.The pharmacogenomics journal · 2002
    Article
12. Multipoint linkage-disequilibrium-mapping approach based on the case-parent trio design.American journal of human genetics · 2001
    Article
13. General equations for Pt, Ps, and the power of the TDT and the affected-sib-pair test.American journal of human genetics · 2000
    Article
14. The problems of using the transmission/disequilibrium test to infer tight linkage.American journal of human genetics · 2000
    Article
15. The role of genetic factors in autoimmune disease: implications for environmental research.Environmental health perspectives · 1999
    Review
16. A note on power approximations for the transmission/disequilibrium test.American journal of human genetics · 1999
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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