ArticleProceedings of the National Academy of Sciences of the United States of America1998
Chemotaxis in a gliding bacterium.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 96 citations in OpenAlex.
- The type IV pilus steering committee: how Pil-Chp controls directional motility.Journal of bacteriology · 2025Review
- Genetic and environmental determinants of streaming and aggregation in Myxococcus xanthus.Scientific reports · 2025Article
- VirB11, a traffic ATPase, mediated flagella assembly and type IV pilus morphogenesis to control the motility and virulence of Xanthomonas albilineans.Molecular plant pathology · 2024Article
- Plasmalogens and Photooxidative Stress Signaling in Myxobacteria, and How it Unmasked CarF/TMEM189 as the Δ1'-Desaturase PEDS1 for Human Plasmalogen Biosynthesis.Frontiers in cell and developmental biology · 2022Review
- Article
- Data-Driven Models Reveal Mutant Cell Behaviors Important for Myxobacterial Aggregation.mSystems · 2020Article
- Bacterial surface motility is modulated by colony-scale flow and granular jamming.Journal of the Royal Society, Interface · 2020Article
- The role of microbial motility and chemotaxis in symbiosis.Nature reviews. Microbiology · 2019Review
- A Nodulation-Proficient Nonrhizobial Inhabitant ofTheScientificWorldJournal · 2019Article
- Agent-Based Modeling Reveals Possible Mechanisms for Observed Aggregation Cell Behaviors.Biophysical journal · 2018Article
- Assessing Travel Conditions: Environmental and Host Influences On Bacterial Surface Motility.Journal of bacteriology · 2018Article
- Data-driven modeling reveals cell behaviors controlling self-organization duringProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Myxobacteria: Moving, Killing, Feeding, and Surviving Together.Frontiers in microbiology · 2016Review
- Directional reversals enable Myxococcus xanthus cells to produce collective one-dimensional streams during fruiting-body formation.Journal of the Royal Society, Interface · 2015Article
- Unlocking the secrets of multi-flagellated propulsion: drawing insights from Tritrichomonas foetus.Journal of the Royal Society, Interface · 2014Article
- Fatty acids from membrane lipids become incorporated into lipid bodies during Myxococcus xanthus differentiation.PloS one · 2014Article
- Diverse populations of lake water bacteria exhibit chemotaxis towards inorganic nutrients.The ISME journal · 2013Article
- Coordinated, long-range, solid substrate movement of the purple photosynthetic bacterium Rhodobacter capsulatus.PloS one · 2011Article
- Statistical image analysis reveals features affecting fates of Myxococcus xanthus developmental aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myxococcus xanthus cells exhibit directed motility up phosphatidylethanolamine (PE) gradients, and we suggest that PE behaves as a chemoattractant. Computer-assisted stop-motion digital microscopy was used to record cell movements in slide culture. PE decreased cellular reversal frequency with molecular specificity that was correlated with the fatty acid composition. Synthetic dilauroyl (di C12:0) PE and dioleoyl (di C18:1 omega9c) PE suppressed direction reversals and stimulated movement up the gradient. Sensory adaptation occurred about 1 hr after the onset of stimulation. Null mutants in a methylated chemotaxis protein homolog (FrzCD) and a CheA/CheY homolog (FrzE) moved up a PE gradient at a reduced rate. The mutants displayed normal excitation but were defective in adaptation. A dominant, hyper-reversal mutant in the M. xanthus methyl accepting chemotaxis protein homolog, frzCD224, failed to respond to PE stimulation, which argued that PE was a transduced stimulus. Neither dilauroyl PE nor dioleoyl PE is present at high enough concentrations in vegetative or developmental PE to account for all of the chemotactic activity. It appears then that there are additional, as yet unknown, PE species that serve as autoattractants. We report on a discrete phospholipid chemoattractant in a gliding bacterium
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.