ArticleProceedings of the National Academy of Sciences of the United States of America1998
Copy number control of a transposable element, the I factor, a LINE-like element in Drosophila.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Review
- The Role of Transposable Elements in Speciation.Genes · 2018Review
- Genomic instability of I elements of Drosophila melanogaster in absence of dysgenic crosses.PloS one · 2010Article
- Small RNAs in the animal gonad: guarding genomes and guiding development.The international journal of biochemistry & cell biology · 2010Review
- Invasion of the Arabidopsis genome by the tobacco retrotransposon Tnt1 is controlled by reversible transcriptional gene silencing.Plant physiology · 2008Article
- A genome-wide transcriptional activity survey of rice transposable element-related genes.Genome biology · 2007Article
- Characterization of active R2 retrotransposition in the rDNA locus of Drosophila simulans.Genetics · 2005Article
- Elimination of foreign DNA during somatic differentiation in Tetrahymena thermophila shows position effect and is dosage dependent.Eukaryotic cell · 2005Article
- Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene.Genetics · 2004Article
- Article
- Two-step regulation and continuous retrotransposition of the rice LINE-type retrotransposon Karma.The Plant cell · 2003Article
- Gene silencing triggered by non-LTR retrotransposons in the female germline of Drosophila melanogaster.Genetics · 2003Article
- COM, a heterochromatic locus governing the control of independent endogenous retroviruses from Drosophila melanogaster.Genetics · 2003Article
- The non-LTR retrotransposons in Ciona intestinalis: new insights into the evolution of chordate genomes.Genome biology · 2003Article
- Article
- Suppressors of transcriptional transgenic silencing in Chlamydomonas are sensitive to DNA-damaging agents and reactivate transposable elements.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Artificial and epigenetic regulation of the I factor, a nonviral retrotransposon of Drosophila melanogaster.Genetics · 2000Article
- New insights on homology-dependent silencing of I factor activity by transgenes containing ORF1 in Drosophila melanogaster.Genetics · 2000Article
- Retrotransposition of the I factor, a non-long terminal repeat retrotransposon of Drosophila, generates tandem repeats at the 3' end.Nucleic acids research · 2000Article
- Determination of L1 retrotransposition kinetics in cultured cells.Nucleic acids research · 2000Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The I factor is a LINE-like transposable element in Drosophila. Most strains of Drosophila melanogaster, inducer strains, contain 10-15 copies of the I factor per haploid genome located in the euchromatic regions of the chromosome arms. These are not present in a few strains known as reactive strains. I factors transpose at low frequency in inducer strains but at high frequency in the female progeny of crosses between reactive and inducer flies. We have found that the activity of the I factor promoter is sensitive to the number of copies of the first 186 nucleotides of the I factor sequence, which constitutes the 5'-untranslated region. The activity of the I factor decreases as the copy number of this sequence increases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.