Evidence map›Paper›PMID 9748464›Full record

ArticleJournal of bacteriology1998

Bradyrhizobium japonicum FixK2, a crucial distributor in the FixLJ-dependent regulatory cascade for control of genes inducible by low oxygen levels.

D Nellen-Anthamatten, P Rossi, O Preisig, I Kullik, M Babst, H M Fischer, H Hennecke

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Reductive evolution and genomic reduction inApplied and environmental microbiology · 2025
    Article
  3. Article
  4. Fine-Tuning Modulation of Oxidation-Mediated Posttranslational Control ofInternational journal of molecular sciences · 2022
    Article
  5. Computationally Reconstructed Interactome ofInternational journal of molecular sciences · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.Microbiology and molecular biology reviews : MMBR · 2017
    Review
  12. FixKFrontiers in microbiology · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

D Nellen-AnthamattenMikrobiologisches Institut, Eidgenössische Technische Hochschule, CH-8092 Zürich, Switzerland.
P Rossi
O Preisig
I Kullik
M Babst
H M Fischer
H Hennecke
Board of the Swiss Federal Institutes of Technology · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bradyrhizobium japonicum possesses a second fixK-like gene, fixK2, in addition to the previously identified fixK1 gene. The expression of both genes depends in a hierarchical fashion on the low-oxygen-responsive two-component regulatory system FixLJ, whereby FixJ first activates fixK2, whose product then activates fixK1. While the target genes for control by FixK1 are unknown, there is evidence for activation of the fixNOQP, fixGHIS, and rpoN1 genes and some heme biosynthesis and nitrate respiration genes by FixK2. FixK2 also regulates its own structural gene, directly or indirectly, in a negative way.

Indexed as

Amino Acid SequenceBacterial ProteinsBase SequenceGene Expression Regulation, BacterialGenes, BacterialHemeproteinsHistidine KinaseModels, GeneticMolecular Sequence DataMutationOperonOxygenRecombinant Fusion ProteinsRestriction MappingRhizobiaceaeSequence Homology, Amino AcidBacterial ProteinsFixJ protein, BacteriaFixK protein, BacteriaFixL protein, BacteriaHemeproteinsHistidine KinaseOxygenRecombinant Fusion Proteins

Identifiers

PMID9748464
PMCPMC107567
OpenAlexW2097480163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.