ArticleJournal of bacteriology1998
CheZ has no effect on flagellar motors activated by CheY13DK106YW.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Deletion of the cheZ gene results in the loss of swimming ability and the decrease of adhesion ability to Caco-2 cells in Escherichia coli Nissle 1917.Folia microbiologica · 2023Article
- Collective motion enhances chemotaxis in a two-dimensional bacterial swarm.Biophysical journal · 2021Article
- Allosteric Priming of E. coli CheY by the Flagellar Motor Protein FliM.Biophysical journal · 2020Article
- Cellular Stoichiometry of Chemotaxis Proteins inJournal of bacteriology · 2020Article
- Robustness in an Ultrasensitive Motor.mBio · 2020Article
- A platform of genetically engineered bacteria as vehicles for localized delivery of therapeutics: Toward applications for Crohn's disease.Bioengineering & translational medicine · 2018Article
- Cellular Stoichiometry of Methyl-Accepting Chemotaxis Proteins in Sinorhizobium meliloti.Journal of bacteriology · 2018Article
- Engineering Bacteria to Search for Specific Concentrations of Molecules by a Systematic Synthetic Biology Design Method.PloS one · 2016Article
- Secondary bacterial flagellar system improves bacterial spreading by increasing the directional persistence of swimming.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Action at a distance: amino acid substitutions that affect binding of the phosphorylated CheY response regulator and catalysis of dephosphorylation can be far from the CheZ phosphatase active site.Journal of bacteriology · 2011Article
- Article
- The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum).Environmental microbiology · 2008Article
- Cellular stoichiometry of the components of the chemotaxis signaling complex.Journal of bacteriology · 2004Article
- Binding of the Escherichia coli response regulator CheY to its target measured in vivo by fluorescence resonance energy transfer.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- A complete sequence of the T. tengcongensis genome.Genome research · 2002Article
- How signals are heard during bacterial chemotaxis: protein-protein interactions in sensory signal propagation.Journal of bacteriology · 2000Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The behaviors of both cheZ-deleted and wild-type cells of Escherichia coli were found to be very sensitive to the level of expression of CheZ, a protein known to accelerate the dephosphorylation of the response regulator CheY-phosphate (CheY-P). However, cells induced to run and tumble by the unphosphorylated mutant protein CheY13DK106YW (CheY**) failed to respond to CheZ, even when CheZ was expressed at high levels. Therefore, CheZ neither affects the flagellar motors directly nor sequesters CheY**. In in vitro cross-linking studies, CheY** promoted trimerization of CheZ to the same extent as wild-type CheY but failed to induce the formation of complexes of higher molecular weight observed with CheY-P. Also, CheY** could be cross-linked to FliM, the motor receptor protein, nearly as well as CheY-P. Thus, to CheZ, CheY** looks like CheY, but to FliM, it looks like CheY-P.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.