SynthesisThorax1998
Parental smoking, bronchial reactivity and peak flow variability in children.
Synthesis in Thorax, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- Health effects of passive smoking. 9. Parental smoking and spirometric indices in children.Thorax · 1998Pooled it
- Effects of COVID-19 pandemic-associated reduction in respiratory infections on infantile asthma development.The journal of allergy and clinical immunology. Global · 2024Article
- Betel Quid Health Risks of Insulin Resistance Diseases in Poor Young South Asian Native and Immigrant Populations.International journal of environmental research and public health · 2020Review
- Secondhand smoke exposure is associated with increased carotid artery intima-media thickness: the Bogalusa Heart Study.Atherosclerosis · 2015Article
- Transgenerational exposure to environmental tobacco smoke.International journal of environmental research and public health · 2014Review
- Interaction between bronchiolitis diagnosed before 2 years of age and socio-economic status for bronchial hyperreactivity.Environmental health and toxicology · 2011Article
- Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan.Respiratory research · 2010Article
- Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness.American journal of respiratory and critical care medicine · 2009Article
- Environmental tobacco smoke (ETS) and respiratory health in children.European journal of pediatrics · 2009Review
- Lung function and bronchial hyper-responsiveness 11 years after hospitalization for bronchiolitis.Acta paediatrica (Oslo, Norway : 1992) · 2007Article
- Analysis and evaluation of environmental tobacco smoke exposure as a risk factor for chronic cough.Cough (London, England) · 2007Article
- How exposure to environmental tobacco smoke, outdoor air pollutants, and increased pollen burdens influences the incidence of asthma.Environmental health perspectives · 2006Review
- Dermal and bronchial symptoms in children: are they caused by PAH containing parquet glue or by passive smoking?International archives of occupational and environmental health · 2005Article
- Assessment of chronic exposure to cigarette smoke and its change during pregnancy by segmental analysis of maternal hair nicotine.Journal of exposure analysis and environmental epidemiology · 2003Article
- Article
- Asthma and indoor environment in Nepal.Thorax · 2001Article
- Review
- Methodology of bronchial responsiveness.Thorax · 1998Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA systematic quantitative review was conducted of the evidence relating environmental tobacco smoke to bronchial hyperresponsiveness (BHR) during childhood.
methodsTwenty-nine relevant studies were identified after consideration of 1593 articles selected by electronic search of the Embase and Medline databases using keywords relevant to passive smoking in children. The search was completed in April 1997.
resultsOf 19 studies using challenge tests in children of school age, 10 (5759 children) could be summarised as the odds ratio of being bronchial hyperreactive in children exposed to environmental tobacco smoke compared with those not exposed. The pooled odds ratio for maternal smoking was 1.29 (95% confidence limits 1.10 to 1.50) with no evidence of heterogeneity between studies. However, in five further studies of 3531 children providing some evidence, but not odds ratios, none were statistically significant. A further four studies on 5233 children have collected data but are not published. In contrast, all four studies of circadian variation in peak expiratory flow found increased variation in children exposed to environmental tobacco smoke.
conclusionsA clear effect of exposure to environmental tobacco smoke on BHR in the general population has not been established. While the meta-analysis suggests a small but real increase in BHR in school aged children, it seems likely that this estimate is biased upwards due to publication bias. In contrast, limited evidence suggests greater variation in peak expiratory flow in children of smoking parents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.