Trial reportBMJ (Clinical research ed.)1998
A multidisciplinary approach for improving services in primary care: randomised controlled trial of screening for haemoglobin disorders.
Trial report in BMJ (Clinical research ed.), 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Educational outreach visits: effects on professional practice and health care outcomes.The Cochrane database of systematic reviews · 2007Pooled it
- Neonatal screening for sickle cell disease.The Cochrane database of systematic reviews · 2000Pooled it
- Systematic review and meta-analysis of practice facilitation within primary care settings.Annals of family medicinePooled it
- The effectiveness of a semi-tailored facilitator-based intervention to optimise chronic care management in general practice: a stepped-wedge randomised controlled trial.BMC family practice · 2014Trial
- A randomised controlled trial of the effect of educational outreach by community pharmacists on prescribing in UK general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2002Trial
- Improving Decision Making about Genetic Testing in the Clinic: An Overview of Effective Knowledge Translation Interventions.PloS one · 2016Review
- Characteristics of Academic Detailing: Results of a Literature Review.American health & drug benefits · 2015Article
- Carrier screening in preconception consultation in primary care.Journal of community genetics · 2012Article
- Parents' experiences of universal screening for haemoglobin disorders: implications for practice in a new genetics era.The British journal of general practice : the journal of the Royal College of General Practitioners · 2008Article
- Genetics support to primary care practitioners - a demonstration project.Journal of genetic counseling · 2007Article
- Haemoglobinopathy screening: an end to institutional racism?The British journal of general practice : the journal of the Royal College of General Practitioners · 2005Article
- Antenatal screening for haemoglobinopathies in primary care: a whole system participatory action research project.The British journal of general practice : the journal of the Royal College of General Practitioners · 2005Article
- Attitudes of potential providers towards preconceptional cystic fibrosis carrier screening.Journal of genetic counseling · 2004Article
- Cost effectiveness of continuing professional development in health care: a critical review of the evidence.BMJ (Clinical research ed.) · 2002Review
- The challenge of integrating genetic medicine into primary care.BMJ (Clinical research ed.) · 2001Review
- Rational or rationed medicine? The promise of genetics for improved clinical practice.BMJ (Clinical research ed.) · 2000Article
- Informed choice in genetic screening for thalassaemia during pregnancy: audit from a national confidential inquiry.BMJ (Clinical research ed.) · 2000Article
- Thalassaemia among Asians in Britain. Thalassaemia Society is working to improve awareness.BMJ (Clinical research ed.) · 1999Article
- Thalassaemia in Britain: a tale of two communities. Births are rising among British Asians but falling in Cypriots.BMJ (Clinical research ed.) · 1998Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo investigate the feasibility of improving screening for carriers of haemoglobin disorders in general practice by using a nurse facilitator to work with primary care teams and the relevant haematology laboratories; to identify problems in communication between all those involved in delivering the service, and to implement solutions.
designTwo year, practice based randomised controlled trial.
settingNorth London area where 29% of residents and 43% of births are in ethnic groups at risk for haemoglobin disorders. SUBJECTS: 26 of the 93 practices using the services of the area's haematology laboratory agreed to take part and were randomly divided into control and intervention practices.
main outcome measureChange in number of requests for screening tests for haemoglobin disorders made by control and intervention practices in baseline and intervention years.
resultsThe number of screening tests requested varied from 0-150 in the 93 practices in the baseline year. Study practices tended to have made a moderate number of requests (10-50) during this period. During the intervention year intervention practices made 292 more requests (99% increase) and control practices made 74 fewer requests (23% decrease; P=0.001 for difference in median change). Four practices, three of which were singlehanded, accounted for 75% of the increase. The number of requests from intervention practices, adjusted for baseline requests, was 3.2 times higher than control practices (P<0.0001).
conclusionGeneral practitioners and practice nurses are willing to undertake a new genetic screening service (or expand an existing one) if they are persuaded that it benefits the health of a significant proportion of their practice population. They need appropriate tools (for example, information materials for carriers and groups at risk), and the laboratory must be sensitive to their needs. Preconceptional carrier screening and counselling need to be coupled with antenatal screening.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.