ArticleJapanese journal of cancer research : Gann1998
Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis.
Article in Japanese journal of cancer research : Gann, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 76 citations in OpenAlex.
- Molecular Approaches to Diagnosis in Ewing Sarcoma: Fluorescence In Situ Hybridization (FISH).Methods in molecular biology (Clifton, N.J.) · 2027Article
- Article
- Pediatric Extra-skeletal Sinonasal Ewing's Sarcoma: Report of Two Cases with Literature Review.Indian journal of surgical oncology · 2024Article
- Ewing Sarcoma of the Vagina: A Rare Clinical Entity.Cureus · 2024Article
- Bioinformatic Analysis of Recurrent Genomic Alterations and Corresponding Pathway Alterations in Ewing Sarcoma.Journal of personalized medicine · 2023Article
- Extensive analysis of 59 sarcoma-related fusion genes identified pazopanib as a potential inhibitor to COL1A1-PDGFB fusion gene.Cancer science · 2023Article
- Identification of a novel translocation producing an in-frame fusion of TAF15 and ETV4 in a case of extraosseous Ewing sarcoma revealed in the prenatal period.Virchows Archiv : an international journal of pathology · 2022Article
- Establishment of multiplex RT-PCR to detect fusion genes for the diagnosis of Ewing sarcoma.Diagnostic pathology · 2021Article
- Molecular Approaches to Diagnosis in Ewing Sarcoma: Fluorescence In Situ Hybridization (FISH).Methods in molecular biology (Clifton, N.J.) · 2021Article
- Article
- Function and regulation of the PEA3 subfamily of ETS transcription factors in cancer.American journal of cancer research · 2020Review
- EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017Article
- Metastatic extraskeletal Ewing's sarcoma treated with trabectedin: A case report.Oncology letters · 2016Article
- Article
- 3D tissue-engineered model of Ewing's sarcoma.Advanced drug delivery reviews · 2014Review
- Clinicopathological and molecular spectrum of ewing sarcomas/PNETs, including validation of EWSR1 rearrangement by conventional and array FISH technique in certain cases.Pathology oncology research : POR · 2014Article
- Molecular diagnosis in Ewing family tumors: the Rizzoli experience--222 consecutive cases in four years.The Journal of molecular diagnostics : JMD · 2011Article
- Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions.The Journal of molecular diagnostics : JMD · 2007Article
- Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.The Journal of molecular diagnostics : JMD · 2007Article
- Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma.Oncogene · 2003Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ewing's sarcoma, one of the most malignant tumors of children and young adults, expresses specific chimeric genes, e.g. EWS-FLI-1, EWS-ERG, EWS-ETV1 and EWS-FEV. In this paper, we extensively characterized a new fusion gene, EWS-EIAF by means of whole cDNA sequencing, RNA blot analysis, DNA blot analysis and chromosomal analysis, and showed it to be available for the diagnosis of Ewing's sarcoma and to participate in the oncogenesis of Ewing's sarcoma. Furthermore, we conducted a genetic analysis of Ewing family tumors in conjunction with immunohistochemical analysis and ultrastructural analysis. Our results demonstrate some limitations of both genetic analysis and histopathological analysis, and establish the relationship between neurogenic phenotypes and chimera genes.
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