ReviewPlant molecular biology1998
Mitochondrial protein import in plants. Signals, sorting, targeting, processing and regulation.
Review in Plant molecular biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 146 citations in OpenAlex.
- Genome-Wide Identification and Expression Analysis of the TIM Gene Family in Sea-Island Cotton (Current issues in molecular biology · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- ATP yield of plant respiration: potential, actual and unknown.Annals of botany · 2023Article
- The roles of plant proteases and protease inhibitors in drought response: a review.Frontiers in plant science · 2023Review
- Protein Processing in Plant Mitochondria Compared to Yeast and Mammals.Frontiers in plant science · 2022Review
- Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana.Journal of experimental botany · 2015Article
- Mitochondrial targeting of the Arabidopsis F1-ATPase γ-subunit via multiple compensatory and synergistic presequence motifs.The Plant cell · 2012Article
- Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization.Molecular biology of the cell · 2011Article
- In silico survey of the mitochondrial protein uptake and maturation systems in the brown alga Ectocarpus siliculosus.PloS one · 2011Article
- Internal architecture of mitochondrial complex I from Arabidopsis thaliana.The Plant cell · 2010Article
- Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins.The Journal of biological chemistry · 2009Article
- Refining the definition of plant mitochondrial presequences through analysis of sorting signals, N-terminal modifications, and cleavage motifs.Plant physiology · 2009Article
- Mitochondrial and nuclear localization of a novel pea thioredoxin: identification of its mitochondrial target proteins.Plant physiology · 2009Article
- Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.Journal of experimental botany · 2009Article
- Efficient mitochondrial targeting relies on co-operation of multiple protein signals in plants.Journal of experimental botany · 2009Article
- Dual targeting of organellar seryl-tRNA synthetase to maize mitochondria and chloroplasts.Plant cell reports · 2008Article
- Lack of respiratory chain complex I impairs alternative oxidase engagement and modulates redox signaling during elicitor-induced cell death in tobacco.The Plant cell · 2007Article
- ND3 and ND4L subunits of mitochondrial complex I, both nucleus encoded in Chlamydomonas reinhardtii, are required for activity and assembly of the enzyme.Eukaryotic cell · 2006Article
- Sequential processing of a mitochondrial tandem protein: insights into protein import in Schizosaccharomyces pombe.Eukaryotic cell · 2006Article
- Adaptations required for mitochondrial import following mitochondrial to nucleus gene transfer of ribosomal protein S10.Plant physiology · 2005Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondrial biogenesis requires a coordinated expression of both the nuclear and the organellar genomes and specific intracellular protein trafficking, processing and assembly machinery. Most mitochondrial proteins are synthesised as precursor proteins containing an N-terminal extension which functions as a targeting signal, which is proteolytically cleaved off after import into mitochondria. We review our present knowledge on components and mechanisms involved in the mitochondrial protein import process in plants. This encompasses properties of targeting peptides, sorting of precursor proteins between mitochondria and chloroplasts, signal recognition, mechanism of translocation across the mitochondrial membranes and the role of cytosolic and organellar molecular chaperones in this process. The mitochondrial protein processing in plants is catalysed by the mitochondrial processing peptidase (MPP), which in contrast to other sources, is integrated into the bc1 complex of the respiratory chain. This is the most studied component of the plant import machinery characterised to date. What are the biochemical consequences of the integration of the MPP into an oligomeric protein complex and how are several hundred presequences of precursor proteins with no sequence similarities and no consensus for cleavage, specifically cleaved off by MPP? Finally we will address the emerging area of the control of protein import into mitochondria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.