ArticleJournal of clinical microbiology1998
Human exposure to a granulocytic Ehrlichia and other tick-borne agents in Connecticut.
Article in Journal of clinical microbiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Global meta-analysis onPathogens and global health · 2022Pooled it
- Global prevalence ofNew microbes and new infections · 2025Article
- The protective effects of BMSA1 and BMSA5-1-1 proteins against Babesia microti infection.Parasites, hosts and diseases · 2024Article
- Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences.Trends in parasitology · 2016Review
- The prevalence of zoonotic tick-borne pathogens in Ixodes scapularis collected in the Hudson Valley, New York State.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2014Article
- Assessment of polymicrobial infections in ticks in New York state.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2010Article
- Multiply infected vectors.Applied and environmental microbiology · 2007Article
- Coinfections acquired from ixodes ticks.Clinical microbiology reviews · 2006Review
- Roles of the Maltese cross form in the development of parasitemia and protection against Babesia microti infection in mice.Infection and immunity · 2003Article
- Surveillance for unexplained deaths and critical illnesses due to possibly infectious causes, United States, 1995-1998.Emerging infectious diseases · 2002Article
- Detection of Ehrlichia chaffeensis DNA in Amblyomma americanum ticks in Connecticut and Rhode Island.Journal of clinical microbiology · 2000Article
- Comparison of two recombinant major outer membrane proteins of the human granulocytic ehrlichiosis agent for use in an enzyme-linked immunosorbent assay.Clinical and diagnostic laboratory immunology · 2000Article
- Serologic diagnosis of Lyme borreliosis by using enzyme-linked immunosorbent assays with recombinant antigens.Journal of clinical microbiology · 2000Article
- Serological expression cloning of novel immunoreactive antigens of Babesia microti.Infection and immunity · 2000Article
- Gamma interferon dominates the murine cytokine response to the agent of human granulocytic ehrlichiosis and helps to control the degree of early rickettsemia.Infection and immunity · 2000Article
- Serology of culture-confirmed cases of human granulocytic ehrlichiosis.Journal of clinical microbiology · 2000Article
- Serodiagnosis of human granulocytic ehrlichiosis by a recombinant HGE-44-based enzyme-linked immunosorbent assay.Journal of clinical microbiology · 1999Article
- Infection with agents of human granulocytic ehrlichiosis, lyme disease, and babesiosis in wild white-footed mice (Peromyscus leucopus) in Connecticut.Journal of clinical microbiology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Indirect fluorescent-antibody (IFA) staining methods with Ehrlichia equi (MRK or BDS strains) and Western blot analyses containing a human granulocytic ehrlichiosis (HGE) agent (NCH-1 strain) were used to confirm probable human cases of infection in Connecticut during 1995 and 1996. Also included were other tests for Ehrlichia chaffeensis, the agent of human monocytic ehrlichiosis (HME), Babesia microti, and Borrelia burgdorferi. Thirty-three (8.8%) of 375 patients who had fever accompanied by marked leukopenia or thrombocytopenia were serologically confirmed as having HGE. Western blot analyses of a subset of positive sera confirmed the results of the IFA staining methods for 15 (78.9%) of 19 seropositive specimens obtained from different persons. There was frequent detection of antibodies to a 44-kDa protein of the HGE agent. Serologic testing also revealed possible cases of Lyme borreliosis (n = 142), babesiosis (n = 41), and HME (n = 21). Forty-seven (26.1%) of 180 patients had antibodies to two or more tick-borne agents. Therefore, when one of these diseases is clinically suspected or diagnosed, clinicians should consider the possibility of other current or past tick-borne infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.