ArticleThe Journal of experimental medicine1978
Acquisition of murine major histocompatibility complex gene products by schistosomula of Schistosoma mansoni.
Article in The Journal of experimental medicine, 1978. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 181 citations in OpenAlex.
- The Biological Significance of Trogocytosis.Results and problems in cell differentiation · 2024Article
- Review
- Behind Enemy Lines: Immunomodulatory Armamentarium of the Schistosome Parasite.Frontiers in immunology · 2020Review
- Article
- Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.Infection and immunity · 2015Article
- Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover.PLoS pathogens · 2010Article
- Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes.PLoS neglected tropical diseases · 2010Article
- Heterogeneity of class I and class II MHC sequences in Schistosoma mansoni.Parasitology research · 2006Article
- Eosinophil activity in Schistosoma mansoni infections in vivo and in vitro in relation to plasma cytokine profile pre- and posttreatment with praziquantel.Clinical and vaccine immunology : CVI · 2006Article
- Cloning and characterization of a gene encoding an immunoglobulin-binding receptor on the cell surface of some members of the family Trypanosomatidae.Infection and immunity · 2003Article
- Receptor for Fc on the surfaces of schistosomes.Infection and immunity · 2001Article
- The immunopathology of siliconosis. History, clinical presentation, and relation to silicosis and the chemistry of silicon and silicone.Immunologic research · 1998Review
- The interaction of human LDL with the tegument of adult Schistosoma mansoni.Molecular and cellular biochemistry · 1997Article
- Potential role for scavenger receptors of human monocytes in the killing of Schistosoma mansoni.The American journal of pathology · 1993Article
- Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma mansoni by release of immunoactive neuropeptides.Proceedings of the National Academy of Sciences of the United States of America · 1992Article
- Role of human decay-accelerating factor in the evasion of Schistosoma mansoni from the complement-mediated killing in vitro.The Journal of experimental medicine · 1991Article
- Specific binding of human low-density lipoprotein to the surface of schistosomula of Schistosoma mansoni and ingestion by the parasite.The American journal of pathology · 1991Article
- Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci.Genetics · 1990Article
- Human lipoprotein binding to schistosomula of schistosoma mansoni. Displacement by polyanions, parasite antigen masking, and persistence in young larvae.The American journal of pathology · 1989Article
- The binding of human low-density lipoproteins to the surface of schistosomula of Schistosoma mansoni is inhibited by polyanions and reduces the binding of anti-schistosomal antibodies.The American journal of pathology · 1989Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schistosoma mansoni schistosomula recovered from the lungs of inbred mice were shown to possess serologically detectable alloantigens on their tegumental surfaces. Using appropriate antisera and infected congenic and recombinant mice as worm donors, gene products of the K and I subregions of the major histocompatibility complex were demonstrated among these alloantigens acquired by the parasites. In contrast, other cell surface alloantigens, such as Thy 1, Ly 1, and H-Y and the serum proteins albumin, C3 and Ig, could not be detected on the surface of lung schistosomula by means of comparable techniques. In another series of experiments, schistosomula recovered from the lungs of mice and reinjected into allogeneic recipients were shown to exchange their alloantigens during an 87-h period of examination. Similarly, lung schistosomula cocultured with allogeneic lymphocytes were shown to acquire major histocompatibility complex (MHC) coded antigens from the cells. It is possible that as acquired host molecules, MHC gene products may disguise the surface of schistosome parasites thereby rendering them insusceptible to immune attack.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.