ArticleJournal of bacteriology1998
Two functionally distinct regions upstream of the cbbI operon of Rhodobacter sphaeroides regulate gene expression.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Article
- CbbR, the Master Regulator for Microbial Carbon Dioxide Fixation.Journal of bacteriology · 2015Review
- Phosphoribulokinase mediates nitrogenase-induced carbon dioxide fixation gene repression in Rhodobacter sphaeroides.Microbiology (Reading, England) · 2015Article
- Amino acid residues of RegA important for interactions with the CbbR-DNA complex of Rhodobacter sphaeroides.Journal of bacteriology · 2014Article
- Regulatory twist and synergistic role of metabolic coinducer- and response regulator-mediated CbbR-cbbI interactions in Rhodopseudomonas palustris CGA010.Journal of bacteriology · 2013Article
- Further unraveling the regulatory twist by elucidating metabolic coinducer-mediated CbbR-cbbI promoter interactions in Rhodopseudomonas palustris CGA010.Journal of bacteriology · 2012Article
- Differential accumulation of form I RubisCO in Rhodopseudomonas palustris CGA010 under Photoheterotrophic growth conditions with reduced carbon sources.Journal of bacteriology · 2009Article
- A novel three-protein two-component system provides a regulatory twist on an established circuit to modulate expression of the cbbI region of Rhodopseudomonas palustris CGA010.Journal of bacteriology · 2006Article
- Identification of genes required for recycling reducing power during photosynthetic growth.Journal of bacteriology · 2005Article
- Effector-mediated interaction of CbbRI and CbbRII regulators with target sequences in Rhodobacter capsulatus.Journal of bacteriology · 2004Article
- RegB/RegA, a highly conserved redox-responding global two-component regulatory system.Microbiology and molecular biology reviews : MMBR · 2004Review
- Research on Carbon Dioxide Fixation in Photosynthetic Microorganisms (1971-present).Photosynthesis research · 2004Article
- Up-regulated expression of the cbb(I) and cbb(II) operons during photoheterotrophic growth of a ribulose 1,5-bisphosphate carboxylase-oxygenase deletion mutant of Rhodobacter sphaeroides.Journal of bacteriology · 2002Article
- Differential expression of the CO2 fixation operons of Rhodobacter sphaeroides by the Prr/Reg two-component system during chemoautotrophic growth.Journal of bacteriology · 2002Article
- Metabolic signals that lead to control of CBB gene expression in Rhodobacter capsulatus.Journal of bacteriology · 2002Article
- Interactive control of Rhodobacter capsulatus redox-balancing systems during phototrophic metabolism.Journal of bacteriology · 2001Article
- Expression of uptake hydrogenase and molybdenum nitrogenase in Rhodobacter capsulatus is coregulated by the RegB-RegA two-component regulatory system.Journal of bacteriology · 2000Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
A number of cbbFI::lacZ translational fusion plasmids containing various lengths of sequence 5' to the form I (cbbI) Calvin-Benson-Bassham cycle operon (cbbFIcbbPIcbbAIcbbLIcbbSI) of Rhodobacter sphaeroides were constructed. Expression of beta-galactosidase was monitored under a variety of growth conditions. It was found that 103 bp of sequence upstream of the cbbFI transcription start was sufficient to confer low levels of regulated cbbI promoter expression; this activity was dependent on the presence of an intact cbbR gene. Additionally, R. sphaeroides CbbR was shown to bind to the region between 9 and 100 bp 5' to the cbbFI transcription start. Inclusion of an additional upstream sequence, from 280 to 636 bp 5' to cbbFI, resulted in a significant increase in regulated cbbI promoter expression under all growth conditions tested. A 50-bp region responsible for the majority of this increase occurs between 280 and 330 bp 5' to cbbFI. The additional 306 bp of upstream sequence from 330 to 636 bp also appears to play a positive regulatory role. A 4-bp deletion 281 to 284 bp 5' to cbbFI significantly reduced cbbI expression while the proper regulatory pattern was retained. These studies provide evidence for the presence of two functionally distinct regions of the cbbI promoter, with the distal domain providing significant regulated promoter activity that adheres to the normal pattern of expression.
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