ArticleJournal of bacteriology1998
A natural large chromosomal inversion in Lactococcus lactis is mediated by homologous recombination between two insertion sequences.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 67 citations in OpenAlex.
- The DigH glycosyl hydrolase is conditionally required for daughter cell separation inJournal of bacteriology · 2025Article
- A 69.9-kb long inverted repeat increases genome instability in a strain ofNAR genomics and bioinformatics · 2025Article
- Article
- NewInternational journal of molecular sciences · 2022Article
- Insertion sequences and other mobile elements associated with antibiotic resistance genes inMicrobial genomics · 2022Article
- Genome rearrangements and megaplasmid loss in the filamentous bacterium Kitasatospora viridifaciens are associated with protoplast formation and regeneration.Antonie van Leeuwenhoek · 2020Article
- Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39.Nucleic acids research · 2018Article
- Disruption of a Transcriptional Repressor by an Insertion Sequence Element Integration Leads to Activation of a Novel Silent Cellobiose Transporter in Lactococcus lactis MG1363.Applied and environmental microbiology · 2017Article
- Flipping chromosomes in deep-sea archaea.PLoS genetics · 2017Article
- Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis.The Journal of biological chemistry · 2016Article
- Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements).Microbial cell factories · 2015Article
- Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli.mBio · 2014Article
- Bacterial genome instability.Microbiology and molecular biology reviews : MMBR · 2014Review
- Host specific diversity in Lactobacillus johnsonii as evidenced by a major chromosomal inversion and phage resistance mechanisms.PloS one · 2011Article
- Chromosomal diversity in Lactococcus lactis and the origin of dairy starter cultures.Genome biology and evolution · 2010Article
- The transposon Galileo generates natural chromosomal inversions in Drosophila by ectopic recombination.PloS one · 2009Article
- Insertion sequence content reflects genome plasticity in strains of the root nodule actinobacterium Frankia.BMC genomics · 2009Article
- Optical mapping reveals a large genetic inversion between two methicillin-resistant Staphylococcus aureus strains.Journal of bacteriology · 2009Article
- Application of physical and genetic map of Rhizobium leguminosarum bv. trifolii TA1 to comparison of three closely related rhizobial genomes.Molecular genetics and genomics : MGG · 2008Article
- Principles of genome evolution in the Drosophila melanogaster species group.PLoS biology · 2007Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comparative analysis of chromosomal macrorestriction polymorphism of the two closely related Lactococcus lactis subsp. cremoris strains MG1363 and NCDO763 revealed the presence of a large inversion covering half of the genome. To determine what kind of genetic element could be implicated in this rearrangement, the two inversion junctions of MG1363 and NCDO763 chromosomes were cloned and characterized. Nucleotide sequence analysis showed the presence of one copy of the lactococcal IS905 element in each junction. Each copy of this element contained the same nucleotide mutation that inactivates the putative transposase. Comparison of the sequences surrounding the insertion sequence demonstrated that the large inversion arose from a single-step homologous recombination event between the two defective copies of the IS905 element. The large inversion presumably conferred no selective disadvantage on strain NCDO763 because this rearrangement did not alter the oriC-terC symmetry of the chromosome and the local genetic environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.