ArticleThe Journal of cell biology1998
The hrp23 protein in the balbiani ring pre-mRNP particles is released just before or at the binding of the particles to the nuclear pore complex.
Article in The Journal of cell biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Imaging Organization of RNA Processing within the Nucleus.Cold Spring Harbor perspectives in biology · 2021Review
- Review
- Specific combinations of SR proteins associate with single pre-messenger RNAs in vivo and contribute different functions.The Journal of cell biology · 2009Article
- A specific SR protein binds preferentially to the secretory protein gene transcripts in salivary glands of Chironomus tentans.Chromosoma · 2006Article
- Chironomus tentans-repressor splicing factor represses SR protein function locally on pre-mRNA exons and is displaced at correct splice sites.Molecular biology of the cell · 2006Article
- Conspicuous accumulation of transcription elongation repressor hrp130/CA150 on the intron-rich Balbiani ring 3 gene.Chromosoma · 2004Article
- An actin-ribonucleoprotein interaction is involved in transcription by RNA polymerase II.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Evidence for a posttranscriptional role of a TFIIICalpha-like protein in Chironomus tentans.Molecular biology of the cell · 2002Article
- Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins.Nucleic acids research · 2002Article
- The mRNA export factor Dbp5 is associated with Balbiani ring mRNP from gene to cytoplasm.The EMBO journal · 2002Article
- A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits.The EMBO journal · 2001Article
- Messenger RNAs are recruited for nuclear export during transcription.Genes & development · 2001Article
- Assembly and transport of a premessenger RNP particle.Proceedings of the National Academy of Sciences of the United States of America · 2001Review
- Actin bound to the heterogeneous nuclear ribonucleoprotein hrp36 is associated with Balbiani ring mRNA from the gene to polysomes.The Journal of cell biology · 2001Article
- The Ct-RAE1 protein interacts with Balbiani ring RNP particles at the nuclear pore.RNA (New York, N.Y.) · 2000Article
- Electron tomography reveals posttranscriptional binding of pre-mRNPs to specific fibers in the nucleoplasm.The Journal of cell biology · 2000Article
- Profilin is associated with transcriptionally active genes.Nucleus (Austin, Tex.)Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Balbiani ring (BR) pre-mRNP particles reside in the nuclei of salivary glands of the dipteran Chironomus tentans and carry the message for giant-sized salivary proteins. In the present study, we identify and characterize a new protein component in the BR ribonucleoprotein (RNP) particles, designated hrp23. The protein with a molecular mass of 20 kD has a single RNA-binding domain and a glycine-arginine-serine-rich auxiliary domain. As shown by immunoelectron microscopy, the hrp23 protein is added to the BR transcript concomitant with transcription, is still present in the BR particles in the nucleoplasm, but is absent from the BR particles that are bound to the nuclear pore complex or are translocating through the central channel of the complex. Thus, hrp23 is released just before or at the binding of the particles to the nuclear pore complex. It is noted that hrp23 behaves differently from two other BR RNP proteins earlier studied: hrp36 and hrp45. These proteins both reach the nuclear pore complex, and hrp36 even accompanies the RNA into the cytoplasm. It is concluded that each BR RNA-binding protein seems to have a specific flow pattern, probably related to the particular role of the protein in gene expression.
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