Evidence map›Paper›PMID 9729454›Full record

ArticleThe Biochemical journal1998

Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists.

J S Marchant, I Parker

Abstract read
In one paragraph

Article in The Biochemical journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. All three IPJournal of cell science · 2018
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J S MarchantDepartment of Pharmacology, University of Cambridge, CB2 1QJ, U.K.
I Parker

Funding

Elementary Events of Intracellular Calcium SignalingR37GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 2011 to 2020
$5.3M
SPATIAL AND TEMPORAL ASPECTS OF INSP3 SIGNALLINGR01GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 1992 to 2010
$3.9M
NIGMS NIH HHS GM 48071Wellcome Trust
6 · The paper itself

Abstract

Elementary Ca2+ puffs form the basic building blocks of global Ins(1, 4,5)P3-evoked Ca2+ signals. In Xenopus oocytes, Ca2+ puffs evoked by the high-affinity agonist adenophostin were shorter and smaller than puffs evoked by Ins(1,4,5)P3 and the lower affinity analogue Ins(2,4, 5)P3. Agonist-specific mechanisms, therefore, play a role in shaping local Ca2+ release events, but termination of Ca2+ flux is not delimited simply by agonist dissociation.

Indexed as

Calcium SignalingAdenosineAnimalsCalcium ChannelsCerebellumFemaleInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsInositol PhosphatesIn Vitro TechniquesKineticsMicroscopy, ConfocalOocytesRatsReceptors, Cytoplasmic and NuclearXenopus laevisadenophostin AAdenosineCalcium ChannelsInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate Receptorsinositol 2,4,5-trisphosphateInositol PhosphatesReceptors, Cytoplasmic and Nuclear

Identifiers

PMID9729454
PMCPMC1219715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.