ArticleThe Journal of cell biology1998
Regulation mechanism of the lateral diffusion of band 3 in erythrocyte membranes by the membrane skeleton.
Article in The Journal of cell biology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 205 citations in OpenAlex.
- Using DNA Origami to Study Nanoscale Organization of Plasma Membranes.Nano letters · 2026Article
- Membrane nanodomains to shape plant cellular functions and signaling.The New phytologist · 2025Review
- Antibody surface mobility amplifies FcγR signaling via Arp2/3 during phagocytosis.Biophysical journal · 2024Article
- Evolution of the Concepts of Architecture and Supramolecular Dynamics of the Plasma Membrane.Membranes · 2023Review
- Cholesterol- and actin-centered view of the plasma membrane: updating the Singer-Nicolson fluid mosaic model to commemorate its 50th anniversaryMolecular biology of the cell · 2023Article
- Article
- A particle-based computational model to analyse remodelling of the red blood cell cytoskeleton during malaria infections.PLoS computational biology · 2022Article
- Cell physiology and molecular mechanism of anion transport by erythrocyte band 3/AE1.American journal of physiology. Cell physiology · 2021Review
- Red Blood Cells: Tethering, Vesiculation, and Disease in Micro-Vascular Flow.Diagnostics (Basel, Switzerland) · 2021Article
- Deformability of Stored Red Blood Cells.Frontiers in physiology · 2021Review
- Theoretical Bases for the Role of Red Blood Cell Shape in the Regulation of Its Volume.Frontiers in physiology · 2020Review
- AMPA receptors in the synapse turnover by monomer diffusion.Nature communications · 2019Article
- Modeling of the axon plasma membrane structure and its effects on protein diffusion.PLoS computational biology · 2019Article
- Synergistic Integration of Laboratory and Numerical Approaches in Studies of the Biomechanics of Diseased Red Blood Cells.Biosensors · 2018Review
- Anti-band 3 and anti-spectrin antibodies are increased in Plasmodium vivax infection and are associated with anemia.Scientific reports · 2018Article
- The Actin/Spectrin Membrane-Associated Periodic Skeleton in Neurons.Frontiers in synaptic neuroscience · 2018Review
- Membrane lipids and cell signaling.Current opinion in lipidology · 2017Review
- Modeling of the axon membrane skeleton structure and implications for its mechanical properties.PLoS computational biology · 2017Article
- Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.Molecular biology of the cell · 2016Article
- Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanisms that regulate the movement of a membrane spanning protein band 3 in erythrocyte ghosts were investigated at the level of a single or small groups of molecules using single particle tracking with an enhanced time resolution (0.22 ms). Two-thirds of band 3 undergo macroscopic diffusion: a band 3 molecule is temporarily corralled in a mesh of 110 nm in diameter, and hops to an adjacent mesh an average of every 350 ms. The rest (one-third) of band 3 exhibited oscillatory motion similar to that of spectrin, suggesting that these band 3 molecules are bound to spectrin. When the membrane skeletal network was dragged and deformed/translated using optical tweezers, band 3 molecules that were undergoing hop diffusion were displaced toward the same direction as the skeleton. Mild trypsin treatment of ghosts, which cleaves off the cytoplasmic portion of band 3 without affecting spectrin, actin, and protein 4.1, increased the intercompartmental hop rate of band 3 by a factor of 6, whereas it did not change the corral size and the microscopic diffusion rate within a corral. These results indicate that the cytoplasmic portion of band 3 collides with the membrane skeleton, which causes temporal confinement of band 3 inside a mesh of the membrane skeleton.
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