ArticleJournal of bacteriology1998
Parallel and divergent genotypic evolution in experimental populations of Ralstonia sp.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens.PLoS biology · 2024Article
- Convergent genetic adaptation ofFrontiers in molecular biosciences · 2024Article
- The evolution of trait correlations constrains phenotypic adaptation to high COProceedings. Biological sciences · 2021Article
- Conserved Metabolic and Evolutionary Themes in Microbial Degradation of Carbamate Pesticides.Frontiers in microbiology · 2021Review
- Trophic network architecture of root-associated bacterial communities determines pathogen invasion and plant health.Nature communications · 2015Article
- Adaptation and heterogeneity of Escherichia coli MC1000 growing in complex environments.Applied and environmental microbiology · 2013Article
- Real time forecasting of near-future evolution.Journal of the Royal Society, Interface · 2012Article
- Replaying the tape of life: quantification of the predictability of evolution.Frontiers in genetics · 2012Article
- Experimental evolution with E. coli in diverse resource environments. I. Fluctuating environments promote divergence of replicate populations.BMC evolutionary biology · 2010Article
- Evolution of efficient pathways for degradation of anthropogenic chemicals.Nature chemical biology · 2009Review
- Short-term genome evolution of Listeria monocytogenes in a non-controlled environment.BMC genomics · 2008Article
- The host acts as a genetic bottleneck during serial infections: an insect-fungal model system.Current genetics · 2006Article
- Loss of expression of cspC, a cold shock family gene, confers a gain of fitness in Escherichia coli K-12 strains.Journal of bacteriology · 2006Article
- Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states.Genome research · 2005Article
- Molecular analysis of bacterial community based on 16S rDNA and functional genes in activated sludge enriched with 2,4-dichlorophenoxyacetic acid (2,4-D) under different cultural conditions.Microbial ecology · 2005Article
- Evolutionary genomics of ecological specialization.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
- Microbial astronauts: assembling microbial communities for advanced life support systems.Microbial ecology · 2004Review
- Dynamics of genome architecture in Rhizobium sp. strain NGR234.Journal of bacteriology · 2002Article
- Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B.Journal of bacteriology · 2001Article
- Substitution, insertion, deletion, suppression, and altered substrate specificity in functional protocatechuate 3,4-dioxygenases.Journal of bacteriology · 1999Article
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Authors and funding
6 authors.
Funding
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Abstract
Genetic rearrangements within a population of bacteria were analyzed to understand the degree of divergence occurring after experimental evolution. We used 18 replicate populations founded from Ralstonia sp. strain TFD41 that had been propagated for 1,000 generations with 2,4-dichlorophenoxyacetic acid (2,4-D) as the carbon source. Genetic divergence was examined by restriction fragment length polymorphism analysis of the incumbent plasmid that carries the 2,4-D catabolic genes and by amplification of random regions of the genome via PCR. In 18 evolved clones examined, we observed duplication within the plasmid, including the tfdA gene, which encodes a 2,4-D dioxygenase that catalyzes the first step in the 2,4-D catabolic pathway. In 71 of 72 evolved clones, a common 2.4-kb PCR product was lost when genomic fingerprints produced by PCR amplification using degenerate primers based on repetitive extragenic palindromic (REP) sequences (REP-PCR) were compared. The nucleotide sequence of the 2.4-kb PCR product has homology to the TRAP (tripartite ATP-independent periplasmic) solute transporter gene family. Hybridization of the 2. 4-kb REP-PCR product from the ancestor to genomic DNA from the evolved populations showed that the loss of the PCR product resulted from deletions in the genome. Deletions in the plasmid and presence and/or absence of other REP-PCR products were also found in these clones but at much lower frequencies. The common and uncommon genetic changes observed show that both parallel and divergent genotypic evolution occurred in replicate populations of this bacterium.
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