Hormone replacement therapy and heart disease prevention: experimentation trumps observation.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. Overweight and effect of hormone replacement therapy on lipid profiles in postmenopausal women.The Korean journal of internal medicine · 2005
   Trial
2. Lung cancer screening in people who have never smoked: lessons from East Asia.BMJ (Clinical research ed.) · 2025
   Article
3. Increased longevity in older users of postmenopausal estrogen therapy: the Leisure World Cohort Study.Menopause (New York, N.Y.) · 2018
   Observational
4. Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study.BMJ (Clinical research ed.) · 2006
   Article
5. Epidemiology of peripheral arterial disease in women.Journal of epidemiology · 2003
   Review
6. Lipid-lowering agents and the risk of hip fracture in a Medicaid population.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2002
   Article
7. 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2002
   Review
8. Postmenopausal hormone replacement therapy and atherosclerosis.Current atherosclerosis reports · 2002
   Review
9. Hormone replacement therapy trials: an update.Current atherosclerosis reports · 2002
   Article
10. [Peer review in scientific journals].Atencion primaria · 2001
    Article
11. Large-scale hormone replacement therapy and life expectancy: results from an international comparison among European and North American populations.American journal of public health · 2000
    Article
12. Hormone replacement therapy: a survey of Ontario physicians' prescribing practices.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 1999
    Article
13. Increased longevity in older users of postmenopausal estrogen therapy: the Leisure World Cohort Study.Menopause (New York, N.Y.)
    Article

Corrections and comments

• Commented on by
  Hormone replacement therapy for secondary prevention of coronary heart disease.1999
• Commented on by
  Hormone replacement therapy for secondary prevention of coronary heart disease.1999
• Commented on by
  Hormone replacement therapy for secondary prevention of coronary heart disease.1999
• Comment on
  Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group.1998

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as