Evidence map›Paper›PMID 9712812›Full record

ArticleInfection and immunity1998

Elevated concentrations of eotaxin and interleukin-5 in human neurocysticercosis.

C A Evans, H H Garcia, A Hartnell, R H Gilman, P J Jose, M Martinez, D G Remick, T J Williams, J S Friedland

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 56 citations in OpenAlex.

  1. Innate Immune Response to Helminth Infections.Advances in experimental medicine and biology · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Do helminths cause epilepsy?Parasite immunology · 2009
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Neurocysticercosis and epilepsy in developing countries.Journal of neurology, neurosurgery, and psychiatry · 2000
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

C A EvansDepartment of Infectious Diseases, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom.
H H Garcia
A Hartnell
R H Gilman
P J Jose
M Martinez
D G Remick
T J Williams
J S Friedland
Imperial College London · GBHammersmith Hospital · GBUniversidad Peruana Cayetano Heredia · PEInstituto Nacional de Ciencias NeurológicasUniversity of Michigan–Ann Arbor · US

Funding

NIGMS NIH HHS GM 44918PHS HHS 1-U01 A135894-01Wellcome Trust
6 · The paper itself

Abstract

Symptomatic neurocysticercosis, a major cause of epilepsy worldwide, results from inflammation around Taenia solium larvae, but the mechanisms are unknown. Eotaxin, not previously reported in cases of human infection, and interleukin-5 (IL-5) but not IL-8 concentrations were elevated in patient serum, and IL-5 levels were also elevated in cerebrospinal fluid (CSF). Eosinophil-selective mediators may be involved in the pathogenesis of cysticercosis. IL-6 concentrations were also elevated in patient CSF, possibly indicative of an acute-phase response.

Indexed as

Chemokines, CCAdultAnimalsChemokine CCL11Chemotactic Factors, EosinophilCysticercosisCytokinesHumansInterleukin-5Middle AgedTaeniaCCL11 protein, humanChemokine CCL11Chemokines, CCChemotactic Factors, EosinophilCytokinesInterleukin-5

Identifiers

PMID9712812
PMCPMC108550
OpenAlexW2168584852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.