ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1998
Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part I: trans-Golgi network-derived organelles undergo regulated exocytosis.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 110 citations in OpenAlex.
- Chronic and Acute Manipulation of Cortical Glutamate Transmission Induces Structural and Synaptic Changes in Co-cultured Striatal Neurons.Frontiers in cellular neuroscience · 2021Article
- Mechanisms and Role of Dendritic Membrane Trafficking for Long-Term Potentiation.Frontiers in cellular neuroscience · 2018Article
- Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP44 through interactions with neuronal scaffold PICK1.FEBS open bio · 2017Article
- Dendritic Release of Neurotransmitters.Comprehensive Physiology · 2016Review
- Multiple signalling modalities mediated by dendritic exocytosis of oxytocin and vasopressin.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Review
- Imaging of kiss-and-run exocytosis of surface receptors in neuronal cultures.Frontiers in cellular neuroscience · 2014Article
- The dendritic SNARE fusion machinery involved in AMPARs insertion during long-term potentiation.Frontiers in cellular neuroscience · 2014Review
- Decreased dendritic spine density as a consequence of tetanus toxin light chain expression in single neurons in vivo.Neuroscience letters · 2013Article
- Postsynaptic kainate receptor recycling and surface expression are regulated by metabotropic autoreceptor signalling.Traffic (Copenhagen, Denmark) · 2013Article
- Dendritic SNAREs add a new twist to the old neuron theory.Proceedings of the National Academy of Sciences of the United States of America · 2011Review
- Dendritic spine formation and synaptic function require neurobeachin.Nature communications · 2011Article
- Colocalization of FM1-43, Bassoon, and GnRH-1: GnRH-1 release from cell bodies and their neuroprocesses.Endocrinology · 2011Article
- Mechanisms and function of dendritic exocytosis.Neuron · 2011Review
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- Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection.Cold Spring Harbor protocols · 2010Article
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- Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains.The Journal of cell biology · 2009Article
- Regulation of dopamine transporter activity by carboxypeptidase E.Molecular brain · 2009Article
- Secretory outposts for the local processing of membrane cargo in neuronal dendrites.Traffic (Copenhagen, Denmark) · 2008Review
- Convergence among non-sister dendritic branches: an activity-controlled mean to strengthen network connectivity.PloS one · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exocytosis is a widely observed cellular mechanism for delivering transmembrane proteins to the cell surface and releasing signaling molecules into the extracellular space. Calcium-evoked exocytosis, traditionally thought to be restricted to presynaptic specializations in neurons, has been described recently in many cells. Here, calcium-evoked dendritic exocytosis (CEDE) is visualized in living cultured hippocampal neurons. Organelles that undergo CEDE are in somata, dendrites, and perisynaptic regions, identified by using immunocytochemistry and correlative light and electron microscopy. CEDE is regulated developmentally: neurons <9 d in vitro do not show CEDE. In addition, CEDE is blocked by tetanus toxin, an inhibitor of regulated exocytosis, and nocodazole, an inhibitor of microtubule polymerization. Organelles that undergo CEDE often are found on the base of spines, putative sites of synaptic plasticity. CEDE therefore could be involved in structural and functional modification of spines and could play a role in synaptic plasticity, where it might involve changes in receptor/channel density, release of active compounds having effect on pre- and postsynaptic function, and/or growth of synaptic structures.
Indexed as
Identifiers
9712651PMC6792980W2120577107What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.