ArticleNucleosides & nucleotides
Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein.
Article in Nucleosides & nucleotides. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Chemical proteomic profiling reveals protein interactors of the alarmones diadenosine triphosphate and tetraphosphate.Nature communications · 2021Article
- Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications.New journal of chemistry = Nouveau journal de chimie · 2010Article
- Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases.Biochemistry · 2002Article
- Di-, tri- and tetra-5'-O-phosphorothioadenosyl substituted polyols as inhibitors of Fhit: Importance of the alpha-beta bridging oxygen and beta phosphorus replacement.BMC chemical biology · 2001Article
- Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates.The Journal of biological chemistry · 2000Article
- The histidine triad superfamily of nucleotide-binding proteins.Journal of cellular physiology · 1999Review
- Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein.Protein engineering · 1997Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The design and synthesis of analogues of diadenosine 5',5"'-P1,P3-triphosphate that are resistant to pyrophosphate hydrolysis is described in relation to their rôle in signalling and tumorigenesis involving the Fhit protein, the human fragile histidine triad protein, which is a novel Ap3A binding/cleaving protein.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.