ArticleProceedings of the National Academy of Sciences of the United States of America1998
Genetically engineered broad-spectrum disease resistance in tomato.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 203 citations in OpenAlex.
- No Cost of Resistance in Wheat Gene Stack Lines Containing 10 Stem Rust Resistance Transgenes.Plant biotechnology journal · 2026Article
- A bacterial CARD-NLR-like immune system controls the release of gene transfer agents.Nature microbiology · 2026Article
- Leaf it to science: Uncovering plant immune systems through technological advances.Plant physiology · 2026Review
- A semi-dominant NLR allele regulates growth and disease resistance in wheat.Plant biotechnology journal · 2025Article
- Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping.Nature plants · 2025Article
- High Basal Expression and Dual Stress Responsiveness of Soybean (Plants (Basel, Switzerland) · 2025Article
- Constitutive Overexpression of an NB-ARC Gene from Wild ChineseInternational journal of molecular sciences · 2024Article
- Structure-function analyses of coiled-coil immune receptors define a hydrophobic module for improving plant virus resistance.Journal of experimental botany · 2023Article
- RXam2, a NLR from cassava (Manihot esculenta) contributes partially to the quantitative resistance to Xanthomonas phaseoli pv. manihotis.Plant molecular biology · 2022Article
- MiR1885 Regulates Disease Tolerance Genes inInternational journal of molecular sciences · 2021Article
- The wheat Sr22, Sr33, Sr35 and Sr45 genes confer resistance against stem rust in barley.Plant biotechnology journal · 2021Article
- The Arabidopsis active demethylase ROS1eLife · 2021Article
- Cognitive and Memory Functions in Plant Immunity.Vaccines · 2020Review
- Ectopic Expression of Grapevine GeneInternational journal of molecular sciences · 2019Article
- Effect of Benzothiadiazole on the Metabolome of Tomato Plants Infected by Citrus Exocortis Viroid.Viruses · 2019Article
- Resistant and susceptible cacao genotypes exhibit defense gene polymorphism and unique early responses to Phytophthora megakarya inoculation.Plant molecular biology · 2019Article
- Enhanced resistance to bacterial and oomycete pathogens by short tandem target mimic RNAs in tomato.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Field grown transgenic Pm3e wheat lines show powdery mildew resistance and no fitness costs associated with high transgene expression.Transgenic research · 2019Article
- Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity.PLoS pathogens · 2018Article
- The Coiled-Coil and Nucleotide Binding Domains of BROWN PLANTHOPPER RESISTANCE14 Function in Signaling and Resistance against Planthopper in Rice.The Plant cell · 2017Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resistance in tomato to the bacterial pathogen Pseudomonas syringae pathovar tomato requires Pto and Prf. Mutations that eliminate Prf show a loss of both Pto resistance and sensitivity to the organophosphate insecticide fenthion, suggesting that Prf controls both phenotypes. Herein, we report that the overexpression of Prf leads to enhanced resistance to a number of normally virulent bacterial and viral pathogens and leads to increased sensitivity to fenthion. These plants express levels of salicylic acid comparable to plants induced for systemic acquired resistance (SAR) and constitutively express pathogenesis related genes. These results suggest that the overexpression of Prf activates the Pto and Fen pathways in a pathogen-independent manner and leads to the activation of SAR. Transgene-induced SAR has implications for the generation of broad spectrum disease resistance in agricultural crop plants.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.