Evidence map›Paper›PMID 9705524›Full record

ArticleNucleic acids research1998

Identification of novel simple sequence length polymorphisms (SSLPs) in mouse by interspersed repetitive element (IRE)-PCR.

J C Detter, Q A Nguyen, S F Kingsmore

Abstract read
In one paragraph

Article in Nucleic acids research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003
    Article
  3. Article
  4. Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2000
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J C DetterDepartment of Medicine and Center for Mammalian Genetics, University of Florida, 1600 SW Archer Road,PO Box 100221, Gainesville, FL 32610, USA. jdetter@nervm.nerdc.ufl.edu
Q A Nguyen
S F Kingsmore

Funding

ISOLATION OF THE CHEDIAK HIGASHI IMMUNE DEFICIENCY GENER01AI039651 · NIAID · UNIVERSITY OF FLORIDA · PI SOUTHWICK, FREDERICK · 1996 to 1999
–
NIAID NIH HHS AI39651
6 · The paper itself

Abstract

Interspersed repetitive element (IRE)-PCR is a useful method for identification of novel human or mouse sequence tagged sites (STSs) from contigs of genomic clones. We describe the use of IRE-PCR with mouse B1 repetitive element primers to generate novel, PCR amplifiable, simple sequence length polymorphisms (SSLPs) from yeast artificial chromosome (YAC) clones containing regions of mouse chromosomes 13 and 14. Forty-two IRE-PCR products were cloned and sequenced from eight YACs. Of these, 29 clones contained multiple simple sequence repeat units. PCR analysis with primers derived from unique sequences flanking the simple sequence repeat units in seven clones showed all to be polymorphic between various mouse strains. This novel approach to SSLP identification represents an efficient method for saturating a genomic interval with polymorphic genetic markers that may expedite the positional cloning of genes for traits and diseases.

Indexed as

Polymorphism, GeneticRepetitive Sequences, Nucleic AcidSequence Tagged SitesAnimalsBase SequenceChromosomes, Artificial, YeastDNA PrimersMiceMice, Inbred StrainsMolecular Sequence DataPolymerase Chain ReactionSpecies SpecificityDNA Primers

Identifiers

PMID9705524
PMCPMC147784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.