ArticleNucleic acids research1998
A hotspot for the Drosophila gypsy retroelement in the ovo locus.
Article in Nucleic acids research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- A mdg4 retrotransposon screen for X-linked female sterile alleles and its relationship with the transcription factor OVO.G3 (Bethesda, Md.) · 2026Article
- AbioRxiv : the preprint server for biology · 2026Article
- Exploring the Relationship of Transposable Elements and Ageing: Causes and Consequences.Genome biology and evolution · 2025Review
- Female germline expression of OVO transcription factor bridges Drosophila generations.G3 (Bethesda, Md.) · 2025Article
- The Rattlesnake W Chromosome: A GC-Rich Retroelement Refugium with Retained Gene Function Across Ancient Evolutionary Strata.Genome biology and evolution · 2022Article
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- Ongoing endeavors to detect mobilization of transposable elements.BMB reports · 2022Review
- Retrovirus reactivation in CHMP2BIntron5 models of frontotemporal dementia.Human molecular genetics · 2020Article
- L1 retrotransposition in the soma: a field jumping ahead.Mobile DNA · 2018Review
- Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Messenger RNA is a functional component of a chromatin insulator complex.EMBO reports · 2013Article
- Evolutionary history of LTR retrotransposon chromodomains in plants.International journal of plant genomics · 2012Article
- Article
- Characterization of ten novel Ty1/copia-like retrotransposon families of the grapevine genome.BMC genomics · 2008Article
- Drosophila couch potato mutants exhibit complex neurological abnormalities including epilepsy phenotypes.Genetics · 2005Article
- Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni.Journal of virology · 2003Article
- Article
- Impact of multiple insertions of two retroelements, ZAM and Idefix at an euchromatic locus.Genetica · 2000Review
- The integration machinery of ZAM, a retroelement from Drosophila melanogaster, acts as a sequence-specific endonuclease.Journal of virology · 1999Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The Drosophila retroelement gypsy has a number of unusual features including an unusual LTR terminal sequence and an apparent target sequence preference. The ovo locus is a known hotspot for gypsy insertion. We examined the target sequence preference of gypsy within ovo by isolating 26 new insertions and sequencing the gypsy/ovo junctions. Insertions were found at multiple sites within the ovo locus. The insertions clustered within an approximately 150 bp region in the non-translated region of the ovo beta transcript, with most insertions falling within the first intron. There were seven sites of insertion within this region and these mostly conform to the consensus sequence YRYRYR (where Y = pyrimidine and R = purine). However, this target sequence is at best necessary but not sufficient to specify a hotspot, as there were several other sequences conforming to this consensus in the ovo locus that were not hit. The results indicate that gypsy may have a higher degree of target specificity than most infectious LTR retroelements.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.