Evidence map›Paper›PMID 9699158›Full record

ArticleThe Journal of orthopaedic and sports physical therapy1998

Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure.

E M Roos, H P Roos, L S Lohmander, C Ekdahl, B D Beynnon

24 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of orthopaedic and sports physical therapy, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 24 registered trials, which are not on this map. Cited by 1,798 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,798citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00332254 phase1 / phase2completednot on this mapstarted 2006, after this paper: background citation

IL-1ra for Prevention of Chondropathy Following Knee Injury

TypeinterventionalSponsorDuke UniversityRan2006 to 2007Enrolled10ConditionsKnee InjuryArmsAnakinra
NCT00435773 phase2completednot on this mapstarted 2004, after this paper: background citation

Single and Repeated Leech Therapy for the Treatment of Late Stage Knee Osteoarthritis. A Randomized, Placebo Controlled Comparative Trial

TypeinterventionalSponsorRWTH Aachen UniversityRan2004 to 2004Enrolled118ConditionsOsteoarthritis, ArthralgiaArmsSingle Leeching, Repeated Leeching after 4 weeks, Placebo Leeching
NCT01032720 naterminatednot on this mapstarted 2010, after this paper: background citation

Ultrasound-guided Versus Sham Ultrasound Corticosteroid Knee Injections

TypeinterventionalSponsorVA Connecticut Healthcare SystemRan2010 to 2012Enrolled33ConditionsOsteoarthritisArmsUltrasound, Sham ultrasound
NCT02025400 phase1completednot on this mapstarted 2012, after this paper: background citation

Phase I Study Comparing Internet Delivered Home Exercise Programs to Standard Orthopedic Care and Outpatient Physical Therapy.

TypeinterventionalSponsorCharlotte Sports Medicine Institute, PARan2012 to 2013Enrolled24ConditionsKnee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus TearArmseRehab, Formal Physical Therapy
NCT02947451 nacompletednot on this mapstarted 2016, after this paper: background citation

Immediate Effects of Manual Therapy Versus TENS in Patients With Knee Osteoarthritis

TypeinterventionalSponsorGabriel Peixoto Leão AlmeidaRan2016 to 2018Enrolled54ConditionsKnee OsteoarthritisArmsManual Therapy, TENS
NCT03008967 completednot on this mapstarted 2016, after this paper: background citation

A Prospective Cohort Study of Patients Undergoing Total Knee and Hip Arthroplasty at a Regional Hospital in Denmark

Typeobservational_patient_registrySponsorBornholms RegionskommuneRan2016 to 2018Enrolled110ConditionsArthroplasty, Replacement, Knee, Arthroplasty, Replacement, HipArmsArthroplasty and postoperative rehabilitation.
NCT03044028 nacompletednot on this mapstarted 2017, after this paper: background citation

Prospective Evaluation of Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)

TypeinterventionalSponsorThe Cleveland ClinicRan2017 to 2018Enrolled66ConditionsArthropathy of Knee JointArmsCyMedica Orthopedics QB1 e-vive™ system
NCT03473821 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Motor Imagery to Facilitate Sensorimotor Relearning (MOTIFS) After ACL Injury: A Randomized Controlled Trial

TypeinterventionalSponsorLund UniversityRan2018 to 2024Enrolled106ConditionsAnterior Cruciate Ligament InjuryArmsMOTIFS
NCT04106986 nacompletednot on this mapstarted 2019, after this paper: background citation

The Effect Of Pulsed Electromagnetic Field And Progressive Resistance Exercise On Knee Osteoarthritis

TypeinterventionalSponsorJordan University of Science and TechnologyRan2019 to 2020Enrolled32ConditionsKnee OsteoarthritisArmsPulsed electromagnetic field and Progressives resistance exercise, PRE
NCT04277676 completednot on this mapstarted 2020, after this paper: background citation

Reliability and Validity of Turkish Version of Knee Injury and Osteoarthritis Outcome Score-12

TypeobservationalSponsorBahçeşehir UniversityRan2020 to 2020Enrolled135ConditionsOsteo Arthritis Knee
NCT04525950 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Robotized Computer Navigation Versus Conventional Technique in Total Knee Replacement. A Randomized, Clinical and Radiostereometric Trial.

TypeinterventionalSponsorHaukeland University HospitalRan2020 to 2031Enrolled214ConditionsArthritis, Degenerative, Osteo Arthritis KneeArmsNavio, Conventional
NCT05204836 phase1terminatednot on this mapstarted 2023, after this paper: background citation

Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention

TypeinterventionalSponsorUniversity of CalgaryRan2023 to 2025Enrolled4ConditionsAnterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis KneeArmsZoledronic Acid Injection, Placebo
NCT05437770 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of Low-intensity Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis - a Randomized Controlled Trial

TypeinterventionalSponsorBispebjerg HospitalRan2022 to 2025Enrolled96ConditionsOsteoarthritis, KneeArmsBFR (Blood-Flow Restricted exercise), Standard rehabilitation
NCT05450458 phase2 / phase3completednot on this mapstarted 2023, after this paper: background citation

Safety and Effectiveness of Hyaluronic Acid and Sorbitol With Overuse Knee Pain in Sportsmen

TypeinterventionalSponsorHospital Regional TlalnepantlaRan2023 to 2025Enrolled64ConditionsOveruse Injury, Body Mass Index in AthletesArmsKNEE JOINT INFILTRATION WITH HYALURONIC ACID WITH SORBITOL SYNOLIS VA
NCT05992064 recruitingnot on this mapstarted 2024, after this paper: background citation

Investigating the Potential of Wearable Sensors for Monitoring the Postoperative Recovery of Total Knee Arthroplasty Patients: A Protocol for Prospective Longitudinal Observational Study

TypeobservationalSponsorAalborg University HospitalRan2024 to 2026Enrolled30ConditionsArthroplasty, Replacement, KneeArmsMeasuring gait
NCT06079684 nacompletednot on this mapstarted 2022, after this paper: background citation

Clinical Evidence Regarding The Dynamic of Baker Cyst Dimensions After Intermittent Vacuum Therapy As Rehabilitation Treatment In Patients With Knee Osteoarthritis

TypeinterventionalSponsorBalnear and Rehabilitation Sanatorium TechirghiolRan2022 to 2022Enrolled65ConditionsBaker Cyst, Knee OsteoarthritisArmsIntermittent vacuum therapy
NCT06195423 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Stop Osteoarthritis (SOAR) Hybrid Effectiveness-Implementation Type 1 Randomized Controlled Trial for Young People At-High-Risk of Early Onset Knee Osteoarthritis

TypeinterventionalSponsorUniversity of British ColumbiaRan2024 to 2028Enrolled210ConditionsKnee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, KneeArmsStop OsteoARthritis (SOAR) program, Living Well after ACLR program
NCT06400329 nacompletednot on this mapstarted 2024, after this paper: background citation

Evaluating the Physiological Impact of Pain Neuroscience Education Versus Standard Education for Older Adults With Osteoarthritis

TypeinterventionalSponsorLisa CarlessoRan2024 to 2025Enrolled37ConditionsOsteoarthritis, Chronic PainArmsPain Neuroscience Education, Standard Pain Education
NCT06726993 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Restricted Kinematic Alignment Versus Unrestricted Kinematic Alignment in Primary Total Knee Arthroplasty:- Randomized Controlled Trial

TypeinterventionalSponsorAssiut UniversityRan2025 to 2027Enrolled80ConditionsOsteoarthritis (OA) of the Knee, Total Knee AnthroplastyArmsTotal knee arthroplasty
NCT07069179 narecruitingnot on this mapstarted 2025, after this paper: background citation

Choose to Move Replacement Ready: A Feasibility Trial of a Virtual Health-promoting Intervention for People Awaiting Total Hip or Knee Replacement Surgery

TypeinterventionalSponsorUniversity of British ColumbiaRan2025 to 2028Enrolled60ConditionsOsteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee ArthroplastyArmsChoose to Move Replacement Ready
NCT07395427 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Comparison of the Effects of Basic Body Awareness Therapy to Conventional Physiotherapy and Home Exercise Program in Individuals With Knee Osteoarthritis

TypeinterventionalSponsorHacettepe UniversityRan2025 to 2026Enrolled63ConditionsKnee OsteoarthritisArmsBBAT plus home exercise programme, Conventional physiotherapy plus home exercise programme, Home exercise programme
NCT07589127 narecruitingnot on this mapstarted 2026, after this paper: background citation

GENicular Nerve Block in KNEE Arthroplasty - The GENKNEE Trial

TypeinterventionalSponsorHelse Møre og Romsdal HFRan2026 to 2029Enrolled70ConditionsOsteoarthritis (OA) of the Knee, Total Knee Arthroplasty, Genicular Nerve BlockArmsPreoperative genicular nerve block (GNB), Placebo nerve block
NCT07688096 phase1 / phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Regenerative Medicine for Joint Hypermobility and Instability: A Prospective, Open-Label, Single-Arm, Step-Care Clinical Study

TypeinterventionalSponsorManhattan Pain Medicine, PLLCRan2026 to 2028Enrolled100ConditionsEhlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint InstabilityArmsDextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational), Visco-3 Sodium Hyaluronate Viscosupplementation
NCT07696650 narecruitingnot on this mapstarted 2026, after this paper: background citation

Choose to Move Replacement Ready: Implementation and Effectiveness of a Virtual Health-Promoting Intervention for People Awaiting Total Hip or Knee Replacement Surgery

TypeinterventionalSponsorUniversity of British ColumbiaRan2026 to 2028Enrolled210ConditionsOsteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee AnthroplastyArmsChoose to Move Replacement Ready
3 · Its place in the literature

Who cites it

1,798 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  5. Clinical relevance of patient-reported outcome measures in the surgical management of focal chondral defects of the knee: a systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026
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  6. The effectiveness of knee bracing in non-operative soft tissue and degenerative knee injuries: A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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1,738 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

E M RoosDepartment of Physical Therapy, University of Lund, Sweden.
H P Roos
L S Lohmander
C Ekdahl
B D Beynnon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is broad consensus that good outcome measures are needed to distinguish interventions that are effective from those that are not. This task requires standardized, patient-centered measures that can be administered at a low cost. We developed a questionnaire to assess short- and long-term patient-relevant outcomes following knee injury, based on the WOMAC Osteoarthritis Index, a literature review, an expert panel, and a pilot study. The Knee injury and Osteoarthritis Outcome Score (KOOS) is self-administered and assesses five outcomes: pain, symptoms, activities of daily living, sport and recreation function, and knee-related quality of life. In this clinical study, the KOOS proved reliable, responsive to surgery and physical therapy, and valid for patients undergoing anterior cruciate ligament reconstruction. The KOOS meets basic criteria of outcome measures and can be used to evaluate the course of knee injury and treatment outcome.

Indexed as

Activities of Daily LivingQuality of LifeAdultAgedFemaleHumansKnee InjuriesLife StyleMaleMiddle AgedOsteoarthritisPain MeasurementPatient ParticipationPilot ProjectsReproducibility of ResultsSensitivity and Specificity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 18 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.