ArticleJournal of virology1998
Classical swine fever virus leader proteinase Npro is not required for viral replication in cell culture.
Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 93 citations in OpenAlex.
- The origins and potential cross-species transmission of paramyxoviruses and other RNA viruses between native snakes and invasive Burmese pythons in the Florida Everglades.Journal of virology · 2026Article
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- Current progress on innate immune evasion mediated by NFrontiers in immunology · 2023Review
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- Bungowannah Pestivirus Chimeras as Novel Double Marker Vaccine Strategy against Bovine Viral Diarrhea Virus.Vaccines · 2022Article
- Genetic diversity and detection of atypical porcine pestivirus infections.Journal of animal science · 2022Article
- A double deletion prevents replication of the pestivirus bovine viral diarrhea virus in the placenta of pregnant heifers.PLoS pathogens · 2021Article
- The Molecular Basis for EViruses · 2021Article
- A positively charged surface patch on the pestivirus NS3 protease module plays an important role in modulating NS3 helicase activity and virus production.Archives of virology · 2021Article
- Article
- Autonomously Replicating RNAs of Bungowannah Pestivirus: EJournal of virology · 2020Article
- Article
- An evolutionary divergent pestivirus lacking the NEmerging microbes & infections · 2019Article
- BVDV Npro protein mediates the BVDV induced immunosuppression through interaction with cellular S100A9 protein.Microbial pathogenesis · 2018Article
- Uncoupling of ProteaseJournal of virology · 2017Article
- Nonreplicative RNA Recombination of an Animal Plus-Strand RNA Virus in the Absence of Efficient Translation of Viral Proteins.Genome biology and evolution · 2017Article
- Pig BVDV-2 non-structural protein (NVirus genes · 2017Article
- Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.Journal of virology · 2014Article
- Npro of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites.Veterinary research · 2014Article
- Crystal structures of the viral protease Npro imply distinct roles for the catalytic water in catalysis.Structure (London, England : 1993) · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sequence encoding the viral leader proteinase Npro was replaced by the murine ubiquitin gene in a full-length cDNA clone of the classical swine fever virus (CSFV) strain Alfort/187. The recombinant virus vA187-Ubi showed growth characteristics similar to those of the parent vA187-1 virus. At two occasions cells infected with vA187-Ubi exhibited a cytopathic effect and were found to contain a subgenomic viral RNA. This RNA lacked the same viral genes as the subgenomic RNA which has been found in all cytopathogenic CSFV strains analyzed so far, but it maintained the ubiquitin sequence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.