ArticleJournal of bacteriology1998
Phosphate assimilation in Rhizobium (Sinorhizobium) meliloti: identification of a pit-like gene.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- PHO1 family members transport phosphate from infected nodule cells to bacteroids in Medicago truncatula.Plant physiology · 2021Article
- Molecular Mechanisms of Phosphate Sensing, Transport and Signalling in Streptomyces and Related Actinobacteria.International journal of molecular sciences · 2021Review
- PhoU Allows Rapid Adaptation to High Phosphate Concentrations by Modulating PstSCAB Transport Rate in Sinorhizobium meliloti.Journal of bacteriology · 2017Article
- Global mapping of transcription start sites and promoter motifs in the symbiotic α-proteobacterium Sinorhizobium meliloti 1021.BMC genomics · 2013Article
- Modulation of rosR expression and exopolysaccharide production in Rhizobium leguminosarum bv. trifolii by phosphate and clover root exudates.International journal of molecular sciences · 2011Article
- The low-affinity phosphate transporter PitA is dispensable for in vitro growth of Mycobacterium smegmatis.BMC microbiology · 2009Article
- Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255.Applied and environmental microbiology · 2006Article
- Regulation and properties of PstSCAB, a high-affinity, high-velocity phosphate transport system of Sinorhizobium meliloti.Journal of bacteriology · 2006Article
- Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria.Nucleic acids research · 2006Article
- Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system.Journal of bacteriology · 2004Article
- Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration.Journal of virology · 2002Article
- Characterization of PitA and PitB from Escherichia coli.Journal of bacteriology · 2001Article
- Transmembrane topology of PiT-2, a phosphate transporter-retrovirus receptor.Journal of virology · 2001Article
- Environmental regulation of exopolysaccharide production in Sinorhizobium meliloti.Journal of bacteriology · 2000Article
- Regulation of stalk elongation by phosphate in Caulobacter crescentus.Journal of bacteriology · 2000Article
- Characterization of two inducible phosphate transport systems in Rhizobium tropici.Applied and environmental microbiology · 2000Article
- A high-density physical map of Sinorhizobium meliloti 1021 chromosome derived from bacterial artificial chromosome library.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Genes coding for phosphotransacetylase and acetate kinase in Sinorhizobium meliloti are in an operon that is inducible by phosphate stress and controlled by phoB.Journal of bacteriology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizobium meliloti mutants defective in the phoCDET-encoded phosphate transport system form root nodules on alfalfa plants that fail to fix nitrogen (Fix-). We have previously reported that two classes of second-site mutations can suppress the Fix- phenotype of phoCDET mutants to Fix+. Here we show that one of these suppressor loci (sfx1) contains two genes, orfA and pit, which appear to form an operon transcribed in the order orfA-pit. The Pit protein is homologous to various phosphate transporters, and we present evidence that three suppressor mutations arose from a single thymidine deletion in a hepta-thymidine sequence centered 54 nucleotides upstream of the orfA transcription start site. This mutation increased the level of orfA-pit transcription. These data, together with previous biochemical evidence, show that the orfA-pit genes encode a Pi transport system that is expressed in wild-type cells grown with excess Pi but repressed in cells under conditions of Pi limitation. In phoCDET mutant cells, orfA-pit expression is repressed, but this repression is alleviated by the second-site suppressor mutations. Suppression increases orfA-pit expression compensating for the deficiencies in phosphate assimilation and symbiosis of the phoCDET mutants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.