ArticleNucleic acids research1998
Direct interaction between Rsc6 and Rsc8/Swh3,two proteins that are conserved in SWI/SNF-related complexes.
Article in Nucleic acids research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- RNA metabolism is the primary target of formamide in vivo.Scientific reports · 2017Article
- MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation.PloS one · 2012Article
- RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks.Molecular and cellular biology · 2011Article
- Involvement of a Toxoplasma gondii chromatin remodeling complex ortholog in developmental regulation.PloS one · 2011Article
- Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.Genetics · 2006Article
- The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks.Molecular and cellular biology · 2005Article
- Genetic analysis of RSC58, which encodes a component of a yeast chromatin remodeling complex, and interacts with the transcription factor Swi6.Molecular genetics and genomics : MGG · 2004Article
- The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion.Molecular and cellular biology · 2004Article
- The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling.The EMBO journal · 2003Article
- Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex.Molecular genetics and genomics : MGG · 2003Article
- The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.Molecular and cellular biology · 2003Article
- HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae.Molecular and cellular biology · 2002Article
- The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities.Genome biology · 2002Article
- Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.The EMBO journal · 1999Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The RSC complex of Saccharomyces cerevisiae is closely related to the SWI/SNF complex. Both complexes are involved in remodeling chromatin structure and they share conserved components. The RSC proteins Sth1, Rsc8/Swh3, Sfh1 and Rsc6 are homologs of the SWI/SNF proteins Swi2/Snf2, Swi3, Snf5 and Swp73 respectively. To investigate the RSC complex, we isolated a temperature-sensitive swh3 allele. A screen for multicopy suppressors yielded plasmids carrying the RSC6 and MAK31 loci. RSC6 also suppressed the formamide sensitivity of a strain with a C-terminal truncation of SWH3 . We show that Swh3 and Rsc6 fusion proteins interact in the two-hybrid system and that the swh3-ts mutation impairs this interaction. Finally, bacterially produced Swh3 and Rsc6 fusion proteins interact in vitro , supporting the genetic evidence for direct interaction between Swh3 and Rsc6 in vivo . We have previously shown that Swh3 also interacts with Sth1. These findings, together with the conservation of these proteins in the SWI/SNF complex and in mammalian SWI/SNF-related complexes, strongly suggest that these proteins form a structural core for the complex.
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