ArticleInfection and immunity1998
Heterogeneous antibody responses in tuberculosis.
Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 1 of them a synthesis that pooled it.
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Who cites it
105 citing papers in PubMed, 1 synthesis or guideline pooled it, 233 citations in OpenAlex.
- Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review.PLoS medicine · 2007Pooled it
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- Evaluation of serological assays for the diagnosis of childhood tuberculosis disease: a study protocol.BMC infectious diseases · 2024Article
- Implications of serological, genomic, and epidemiological insights intoFrontiers in tuberculosis · 2024Article
- Antibodies as key mediators of protection againstFrontiers in immunology · 2024Review
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- Profiling of Humoral Immune Response in Typhoid Patients against Differentially Extracted Whole Cell Bacterial Protein Derived fromInterdisciplinary perspectives on infectious diseases · 2023Article
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- Antibodies as clinical tools for tuberculosis.Frontiers in immunology · 2023Review
- Differential levels of anti-Frontiers in medicine · 2023Article
- Unbalanced serum immunoglobulins in clinical subtypes of pediatric tuberculosis disease.Frontiers in pediatrics · 2022Article
- Distinct and shared B cell responses of tuberculosis patients and their household contacts.PloS one · 2022Article
- Antibody Subclass and Glycosylation Shift Following Effective TB Treatment.Frontiers in immunology · 2021Article
- Serum proteomic analysis ofThe Journal of international medical research · 2020Article
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- Immunology ofMicrobiology spectrum · 2019Review
- An Observational Case-Control Study to Determine Human Immunodeficiency Virus and Host Factor Influence on Biomarker Distribution and Serodiagnostic Potential in Adult Pulmonary Tuberculosis.Tropical medicine and infectious disease · 2019Article
- Models of immune selection for multi-locus antigenic diversity of pathogens.Nature reviews. Immunology · 2019Review
- Modeling the Accuracy of TwoFrontiers in veterinary science · 2019Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Antibody responses during tuberculosis were analyzed by an enzyme-linked immunosorbent assay with a panel of 10 protein antigens of Mycobacterium tuberculosis. It was shown that serum immunoglobulin G antibodies were produced against a variety of M. tuberculosis antigens and that the vast majority of sera from tuberculosis patients contained antibodies against one or more M. tuberculosis antigens. The number and the species of serologically reactive antigens varied greatly from individual to individual. In a given serum, the level of specific antibodies also varied with the antigen irrespective of the total number of antigens recognized by that particular serum. These findings indicate that person-to-person heterogeneity of antigen recognition, rather than recognition of particular antigens, is a key attribute of the antibody response in tuberculosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.