ArticleAntimicrobial agents and chemotherapy1998
Energy-dependent accumulation of fluoroquinolones in quinolone-resistant Klebsiella pneumoniae strains.
Article in Antimicrobial agents and chemotherapy, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 48 citations in OpenAlex.
- Prediction of Fluoroquinolone Susceptibility Directly from Whole-Genome Sequence Data by Using Liquid Chromatography-Tandem Mass Spectrometry To Identify Mutant Genotypes.Antimicrobial agents and chemotherapy · 2018Article
- Plasmid-mediated quinolone resistance (PMQR) and mutations in the topoisomerase genes of Salmonella enterica strains from Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013Article
- Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence.Antimicrobial agents and chemotherapy · 2010Article
- Extended-spectrum β-lactamases producing Klebsiella pneumoniae isolated in two hospitals in Goiânia/Brazil: detection, prevalence, antimicrobial susceptibility and molecular typing.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2008Article
- Alteration of GyrA amino acid required for ciprofloxacin resistance in Klebsiella pneumoniae isolates in China.Antimicrobial agents and chemotherapy · 2008Article
- Fluoroquinolone resistance in Haemophilus influenzae is associated with hypermutability.Antimicrobial agents and chemotherapy · 2007Article
- Inhibition of gene expression and growth by antisense peptide nucleic acids in a multiresistant beta-lactamase-producing Klebsiella pneumoniae strain.Antimicrobial agents and chemotherapy · 2007Article
- Quinolones sensitize gram-negative bacteria to antimicrobial peptides.Antimicrobial agents and chemotherapy · 2006Article
- Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance.Antimicrobial agents and chemotherapy · 2003Article
- Role of AcrR and ramA in fluoroquinolone resistance in clinical Klebsiella pneumoniae isolates from Singapore.Antimicrobial agents and chemotherapy · 2003Article
- Patterns of resistance associated with integrons, the extended-spectrum beta-lactamase SHV-5 gene, and a multidrug efflux pump of Klebsiella pneumoniae causing a nosocomial outbreak.Journal of clinical microbiology · 2003Article
- Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum beta-lactamase production.Antimicrobial agents and chemotherapy · 2002Article
- Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria.Antimicrobial agents and chemotherapy · 2000Review
- Energy-dependent accumulation of fluoroquinolones in quinolone-resistant Klebsiella pneumoniae strains.Antimicrobial agents and chemotherapy · 1998Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intracellular accumulation of norfloxacin and pefloxacin in Klebsiella pneumoniae was evaluated. The roles of lipopolysaccharide, capsule, and outer membrane proteins were not important for the intrabacterial accumulation of fluoroquinolones in isogenic strains with known outer membrane alterations. In fluoroquinolone-resistant clinical isolates also expressing GyrA alterations, an active efflux leading to decreased accumulation of the drugs enhanced their resistance to these agents.
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Registered trials
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