ArticleJournal of clinical pathology1998
Fine needle aspiration cytology in the investigation on non-Hodgkin's lymphoma.
Article in Journal of clinical pathology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Analysis of Under-Diagnosed Malignancy during Fine Needle Aspiration Cytology of Lymphadenopathies.International journal of molecular sciences · 2023Article
- Diffuse Large B-Cell Lymphoma of Thyroid: A Case Report and Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Deep convolutional neural network Inception-v3 model for differential diagnosing of lymph node in cytological images: a pilot study.Annals of translational medicine · 2019Article
- Flow immunophenotyping of benign lymph nodes sampled by FNA: Representative with diagnostic pitfalls.Cancer cytopathology · 2018Article
- Value of fine needle aspiration cell blocks in the diagnosis and classification of lymphoma.International journal of clinical and experimental pathology · 2014Article
- Diagnosis of B-cell non-hodgkin lymphomas with small-/intermediate-sized cells in cytopathology.Pathology research international · 2012Article
- Flow cytometric immunophenotyping (FCI) of lymphoma: correlation with histopathology and immunohistochemistry.Diagnostic pathology · 2008Article
- Ki-67 proliferative marker in lymph node aspirates of patients with non-Hodgkin's lymphoma.Medical oncology (Northwood, London, England) · 2006Article
- Primary thyroid lymphomas.Current treatment options in oncology · 2004Review
- Immunoflow cytometry and cell block immunohistochemistry in the FNA diagnosis of lymphoma: a review of 73 consecutive cases.Journal of clinical pathology · 2000Article
- Fine needle aspiration of lymph nodes.Journal of clinical pathology · 1998Review
- Fine needle aspiration and the diagnosis of non-Hodgkin's lymphoma.Journal of clinical pathology · 1998Article
- Fine needle aspiration cytology in the evaluation of lymphoid lesions: a retrospective study of the utility of flow cytometry in conjunction with morphology.Annals of Saudi medicineArticle
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4 authors.
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Abstract
aimsTo assess the value of flow cytometry (FCM) in the diagnosis and classification of reactive lymphoid hyperplasia and malignant lymphoma by fine needle aspiration (FNA) cytology.
methodsForty six fine needle aspirates of lymphoproliferative disorders were examined by FCM as well as routine cytological assessment. An immunoglobulin light chain ratio (LCR) was calculated for clonality analysis. Additional immunophenotyping was performed in 15 cases.
resultsAll 25 cases of reactive lymphoid hyperplasia were polyclonal by FCM (LCR < 2/1); 17 of 20 cases of B cell non-Hodgkin's lymphoma were monoclonal (LCR > 3/1). Analysis of cells based on size facilitated detection of small populations of clonal neoplastic cells. Analysis of CD5, CD10, and CD23 expression by FCM facilitated subclassification of mantle cell lymphoma, small lymphocytic lymphoma, and some lymphomas of follicle centre cell origin. One case of T cell non-Hodgkin's lymphoma was correctly classified by FCM.
conclusionsFNA cytology is a reliable method for investigation of lymphoproliferative disorders. Although excision biopsy and histopathological examination remain the gold standard for primary diagnosis and classification of non-Hodgkin's lymphoma, FNA cytology with clonality analysis and immunophenotyping by FCM is useful for distinguishing reactive from neoplastic lymphoid populations, and can facilitate lymphoma classification.
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