Evidence map›Paper›PMID 9638475›Full record

ReviewImmunologic research1998

The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions.

J S Hayflick, P Kilgannon, W M Gallatin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Association between theBioscience reports · 2019
    Pooled it
  2. Pooled it
  3. Intercellular adhesion molecule-1 K469E polymorphism and risk of coronary artery disease: a meta-analysis.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Pooled it
  4. Pooled it
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  18. Gene variants as risk factors for gastroschisis.American journal of medical genetics. Part A · 2016
    Article
  19. Hypoxia: The Force that Drives Chronic Kidney Disease.Clinical medicine & research · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J S HayflickICOS Corp., Bothell, WA 98021, USA. jhayflick@icos.com
P Kilgannon
W M Gallatin
EKOS Corporation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macromolecular adhesive associations between cells are important for transmitting spatial and temporal information that is critical for immune system function. One such group of proteins, the intercellular adhesion molecules (ICAMs), has grown as newly identified members are revealed. In addition, the functions of the ICAMs, in general, have begun to be better understood, including intracellular signaling events. This information has led to the design of novel therapeutic agents that may prove effective in a variety of disease states.

Indexed as

Antigens, DifferentiationAmino Acid SequenceAntigens, CDCell Adhesion MoleculesCell CommunicationConserved SequenceCytoplasmDrug DesignHumansIntercellular Adhesion Molecule-1Membrane GlycoproteinsNerve Tissue ProteinsSequence Homology, Amino AcidAntigens, CDAntigens, DifferentiationCell Adhesion MoleculesICAM2 protein, humanICAM3 protein, humanICAM4 protein, humanICAM5 protein, humanIntercellular Adhesion Molecule-1Membrane GlycoproteinsNerve Tissue Proteins

Identifiers

PMID9638475
OpenAlexW1968098105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.