ReviewEnvironmental health perspectives1998
The Environmental Genome Project: functional analysis of polymorphisms.
Review in Environmental health perspectives, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- The contribution of the exposome to the burden of cardiovascular disease.Nature reviews. Cardiology · 2023Review
- Inherited alterations of TGF beta signaling components in Appalachian cervical cancers.Cancer causes & control : CCC · 2019Article
- Innovative strategies for annotating the "relationSNP" between variants and molecular phenotypes.BioData mining · 2019Review
- Considerations for Using Genetic and Epigenetic Information in Occupational Health Risk Assessment and Standard Setting.Journal of occupational and environmental hygiene · 2015Article
- Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes.Biomarker insights · 2012Article
- The Environmental Polymorphism Registry: a unique resource that facilitates translational research of environmental disease.Environmental health perspectives · 2011Article
- Gene-environment interactions in the development of complex disease phenotypes.International journal of environmental research and public health · 2008Article
- The Environmental Polymorphisms Registry: a DNA resource to study genetic susceptibility loci.Human genetics · 2008Article
- Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.American journal of human genetics · 2008Article
- Genetic tests of biologic systems in affective disorders.Molecular psychiatry · 2005Review
- Promoting comparative molecular studies in environmental health research: an overview of the comparative toxicogenomics database (CTD).The pharmacogenomics journal · 2004Review
- An occupational reproductive research agenda for the third millennium.Environmental health perspectives · 2003Article
- Application of genomics to toxicology research.Environmental health perspectives · 2002Review
- Postgenomic chemical ecology: from genetic code to ecological interactions.Journal of chemical ecology · 2002Review
- A bold new direction for environmental health research.American journal of public health · 2001Article
- Toxicogenomics: "the call of the wild chip".Environmental health perspectives · 2001Article
- Pharmacogenomics: the promise of personalized medicine.AAPS pharmSci · 2000Review
- Pharmacogenomics. Interview by Clare Thompson.BMJ (Clinical research ed.) · 1999Article
- Pharmacogenomics.The Western journal of medicine · 1999Article
- Human exposure assessment and the National Toxicology Program.Environmental health perspectives · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The ultimate goal of the Environmental Genome Project is the improvement of human health on the basis of information about the variations in certain genes. The first phase of the project will involve the selection of the human genes and characterization of the alleles occurring in the American population. However, intelligent use of this information will require analysis of the relevance of the allelic differences. Epidemiology alone will not solve the problem, and mechanistic studies will be required. Factors to be considered in the design of functional analyses are considered in this commentary.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.