J-curve not burned off by HOT study. Hypertension Optimal Treatment.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Diastolic blood pressure levels and ischemic stroke incidence in older adults with white matter lesions.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011
   Article
2. Commentary: counterpoint. Simple-minded antihypertensive treatment: of assumptions, potpourri, and sausages.Journal of clinical hypertension (Greenwich, Conn.) · 2009
   Article
3. [Arterial hypertension and dementia].Der Nervenarzt · 2005
   Review
4. The Hypertension Optimal Treatment Study: what did it give us?Current hypertension reports · 1999
   Article
5. Intensive antihypertensive treatment to the new lower blood pressure targets.Current hypertension reports · 1999
   Review
6. Renal protection and antihypertensive drugs: current status.Drugs · 1999
   Review
7. The need for evidence in hypertension management: historical perspective.Annals of Saudi medicine
   Review
8. Beyond the usual strategies for blood pressure reduction: therapeutic considerations and combination therapies.Journal of clinical hypertension (Greenwich, Conn.)
   Review

Corrections and comments

• Comment on
  Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.1998

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as