ArticleInfection and immunity1998
Attachment of Cryptosporidium parvum sporozoites to human intestinal epithelial cells.
Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 51 citations in OpenAlex.
- The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.Scientific reports · 2023Article
- Early immune and host cell responses toFrontiers in parasitology · 2023Article
- Calcium-Mediated Biophysical Binding of Cryptosporidium parvum Oocysts to Surfaces Is Sensitive to Oocyst Age.Applied and environmental microbiology · 2019Article
- The Cryptosporidium parvum C-Type Lectin CpClec Mediates Infection of Intestinal Epithelial Cells via Interactions with Sulfated Proteoglycans.Infection and immunity · 2016Article
- Characterization of the carbohydrate components of Taenia solium oncosphere proteins and their role in the antigenicity.Parasitology research · 2013Article
- Standardization of a fluorescent-based quantitative adhesion assay to study attachment of Taenia solium oncosphere to epithelial cells in vitro.Journal of immunological methods · 2012Article
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- The cell biology of cryptosporidium infection.Microbes and infection · 2011Review
- Quantification of in vitro and in vivo Cryptosporidium parvum infection by using real-time PCR.Applied and environmental microbiology · 2006Article
- Interaction of Cryptosporidium hominis and Cryptosporidium parvum with primary human and bovine intestinal cells.Infection and immunity · 2006Article
- Microbial adhesion of Cryptosporidium parvum sporozoites: purification of an inhibitory lipid from bovine mucosa.The Journal of parasitology · 2004Article
- The role of Cryptosporidium parvum-derived phospholipase in intestinal epithelial cell invasion.Parasitology research · 2003Article
- Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis.Antimicrobial agents and chemotherapy · 2002Article
- Characterization of an intestinal epithelial cell receptor recognized by the Cryptosporidium parvum sporozoite ligand CSL.Infection and immunity · 2001Article
- Mediation of Cryptosporidium parvum infection in vitro by mucin-like glycoproteins defined by a neutralizing monoclonal antibody.Infection and immunity · 2000Article
- Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15.Infection and immunity · 2000Article
- Intestinal epithelial cell apoptosis following Cryptosporidium parvum infection.Infection and immunity · 2000Article
- Human intestinal and biliary cryptosporidiosis.World journal of gastroenterology · 1999Article
- Cryptosporidium parvum apical complex glycoprotein CSL contains a sporozoite ligand for intestinal epithelial cells.Infection and immunity · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
An enzyme-linked immunosorbent assay-based attachment model using the human intestinal cell line Caco-2A was developed to study attachment of Cryptosporidium parvum sporozoites in vitro and to assess potential inhibitors of sporozoite binding. In this system, attachment was related to sporozoite dose, incubation time, and host cell differentiation status. Polyclonal antibodies to C. parvum as well as glycoprotein inhibitors of a sporozoite lectin reduced attachment. This model will be a valuable tool in elucidating specific molecules and mechanisms involved in sporozoite-host cell attachment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.