ArticleNucleic acids research1998
Multilevel regulation of histone gene expression during the cell cycle in tobacco cells.
Article in Nucleic acids research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- RicePlant biotechnology (Tokyo, Japan) · 2024Article
- Identification and characterization of histones inNAR genomics and bioinformatics · 2021Article
- High Concentration of Melatonin Regulates Leaf Development by Suppressing Cell Proliferation and Endoreduplication in Arabidopsis.International journal of molecular sciences · 2017Article
- Identification and Characterization of Switchgrass Histone H3 and CENH3 Genes.Frontiers in plant science · 2016Article
- A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription.Molecular plant · 2013Article
- miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis.Journal of experimental botany · 2011Article
- Ribonucleotide reductase regulation in response to genotoxic stress in Arabidopsis.Plant physiology · 2009Article
- Two-Step Regulation of LAX PANICLE1 Protein Accumulation in Axillary Meristem Formation in Rice.The Plant cell · 2009Article
- Molecular cloning and gene expression of a fibrillarin homolog of tobacco BY-2 cells.Protoplasma · 2006Article
- The balance between cell division and endoreplication depends on E2FC-DPB, transcription factors regulated by the ubiquitin-SCFSKP2A pathway in Arabidopsis.The Plant cell · 2006Article
- Constitutive expression exposes functional redundancy between the Arabidopsis histone H2A gene HTA1 and other H2A gene family members.The Plant cell · 2006Article
- Role of an atypical E2F transcription factor in the control of Arabidopsis cell growth and differentiation.The Plant cell · 2004Article
- Fertilization induces strong accumulation of a histone deacetylase (HD2) and of other chromatin-remodeling proteins in restricted areas of the ovules.Plant molecular biology · 2003Article
- Quantitative cDNA-AFLP analysis for genome-wide expression studies.Molecular genetics and genomics : MGG · 2003Article
- Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(AtSKP2) pathway in response to light.The Plant cell · 2002Article
- Expression and stability of Arabidopsis CDC6 are associated with endoreplication.The Plant cell · 2001Article
- Cell cycle regulation of the tobacco ribonucleotide reductase small subunit gene is mediated by E2F-like elements.The Plant cell · 2000Article
- Expression of ZmMET1, a gene encoding a DNA methyltransferase from maize, is associated not only with DNA replication in actively proliferating cells, but also with altered DNA methylation status in cold-stressed quiescent cells.Nucleic acids research · 2000Article
- Histone synthesis in Leishmania infantum is tightly linked to DNA replication by a translational control.The Biochemical journal · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The respective involvement of transcriptional and post-transcriptional mechanisms in coupling H3 and H4 histone gene expression to the S phase of the cell cycle has been studied in synchronized tobacco cells. Induction of histone gene expression at the G1/S transition is shown to be essentially directed by an increase in the transcription rate in response to cellular signals occurring at the initiation step of DNA replication. Histone gene induction thus precedes the burst of DNA synthesis. However, when the elongation step of DNA replication is ineffective or artificially arrested, feedback mechanisms apparently act at the translation level to avoid overproduction of histone proteins from their mRNAs. At the end of S phase, post-transcriptional mechanisms ensure a rapid degradation of histone mRNAs. Transcription factors are bound to the cis -elements of histone promoters throughout the cell cycle, thus suggesting a post-translational modification of some of them to trigger promoter activation at the G1/S transition. Based on these results, a model is proposed for histone gene transcriptional induction in connection with the components of the cell cycle machinery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.