Evidence map›Paper›PMID 9624507›Full record

ArticleAntimicrobial agents and chemotherapy1998

In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae.

P M Roblin, M R Hammerschlag

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  9. Review
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  11. Article
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  13. Article
  14. Telithromycin.Drugs · 2004
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Telithromycin.Drugs · 2001
    Article
  20. Macrolide resistance conferred by base substitutions in 23S rRNA.Antimicrobial agents and chemotherapy · 2001
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P M RoblinDepartment of Pediatrics, SUNY Health Science Center at Brooklyn, New York 11203, USA.
M R Hammerschlag

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro activities of HMR 3647, roxithromycin, erythromycin, and azithromycin against 19 strains of Chlamydia pneumoniae were tested. The MIC at which 90% of the isolates are inhibited and the minimum bactericidal concentration at which 90% of the isolates are killed of HMR 3647 were 0.25 microgram/ml (range, 0.015 to 2 micrograms/ml). Nine recently obtained clinical isolates from children with pneumonia were more susceptible (MICs, 0.015 to 0.0625 microgram/ml) than older strains that had been passaged more extensively.

Indexed as

KetolidesMacrolidesAnti-Bacterial AgentsAzithromycinChildChild, PreschoolChlamydophila pneumoniaeErythromycinHumansMicrobial Sensitivity TestsRoxithromycinAnti-Bacterial AgentsAzithromycinErythromycinKetolidesMacrolidesRoxithromycintelithromycin

Identifiers

PMID9624507
PMCPMC105635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.