Evidence map›Paper›PMID 9621082›Full record

ArticleJournal of virology1998

Enhanced gene transfer with fusogenic liposomes containing vesicular stomatitis virus G glycoprotein.

A Abe, A Miyanohara, T Friedmann

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Targeting the Inside of Cells with Biologicals: Chemicals as a Delivery Strategy.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2021
    Review
  4. Review
  5. Review
  6. Secretory Nanoparticles ofNanomaterials (Basel, Switzerland) · 2019
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

A AbeDepartment of Pediatrics, Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093-0634, USA.
A Miyanohara
T Friedmann
University of California, San Diego · US

Funding

GENE THERAPY OF HYPERCHOLESTEROLEMIAR01DK049023 · NIDDK · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI FRIEDMANN, THEODORE · 1995 to 1998
–
RETROVIRAL VECTOR BASED GENE THERAPY FOR HEMOPHILIA BR01HL053680 · NHLBI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI FRIEDMANN, THEODORE · 1994 to 1998
–
NHLBI NIH HHS HL53680NIDDK NIH HHS DK49023
6 · The paper itself

Abstract

Exposure of Lipofectin-DNA complexes to the partially purified G glycoprotein of the vesicular stomatitis virus envelope (VSV-G) results in loss of serum-mediated inhibition and in enhanced efficiency of gene transfer. Sucrose density gradient sedimentation analysis indicated that the VSV-G associates physically with the DNA-lipid complex to produce a VSV-G liposome. The ability to incorporate surrogate viral or cellular envelope components such as VSV-G into liposomes may allow more-efficient and possibly targeted gene delivery by lipofection, both in vitro and in vivo.

Indexed as

Gene Transfer TechniquesMembrane GlycoproteinsCulture MediaDNA, ViralLiposomesPhosphatidylethanolaminesTransfectionViral Envelope Proteins1,2-dielaidoylphosphatidylethanolamineCulture MediaDNA, ViralG protein, vesicular stomatitis virusLiposomesMembrane GlycoproteinsPhosphatidylethanolaminesViral Envelope Proteins

Identifiers

PMID9621082
PMCPMC110424
OpenAlexW2147579354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.