Mind the GAP, Rho, Rab and GDI.

S E Antonarakis, L Van Aelst

Abstract readCommentNews

In one paragraph

Article in Nature genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

Structural basis of membrane trafficking by Rab family small G protein.International journal of molecular sciences · 2013
Review
PAK in Alzheimer disease, Huntington disease and X-linked mental retardation.Cellular logistics · 2012
Article
Spatial cycles in G-protein crowd control.The EMBO journal · 2010
Review
Strong synaptic transmission impact by copy number variations in schizophrenia.Proceedings of the National Academy of Sciences of the United States of America · 2010
Article
The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation.Proceedings of the National Academy of Sciences of the United States of America · 2002
Article
Targeting fragile X.Genome biology · 2002
Review
Two unrelated patients with inversions of the X chromosome and non-specific mental retardation: physical and transcriptional mapping of their common breakpoint region in Xq13.1.Journal of medical genetics · 1999
Article
How to get to the right place at the right time: Rab/Ypt small GTPases and vesicle transport.Protoplasma · 1999
Article

4 · The record

Corrections and comments

Comment on
Mutations in GDI1 are responsible for X-linked non-specific mental retardation.1998

5 · Who and what money

Authors and funding

2 authors.

S E Antonarakis

L Van Aelst

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Guanine Nucleotide Dissociation InhibitorsMutationAnimalscdc42 GTP-Binding ProteinCell Cycle ProteinsGenetic LinkageGTP-Binding ProteinsGTP PhosphohydrolasesHumansIntellectual DisabilityNerve Tissue ProteinsProto-Oncogene Proteinsrab3 GTP-Binding Proteinsrac GTP-Binding ProteinsrhoA GTP-Binding ProteinX Chromosomecdc42 GTP-Binding ProteinCell Cycle ProteinsGDP dissociation inhibitor 1GTP-Binding ProteinsGTP PhosphohydrolasesGuanine Nucleotide Dissociation InhibitorsNerve Tissue ProteinsProto-Oncogene Proteinsrab3 GTP-Binding Proteinsrac GTP-Binding ProteinsrhoA GTP-Binding Protein

Identifiers

PMID9620758

DOI10.1038/450

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.