Evidence map›Paper›PMID 9620370›Full record

ArticleJournal of clinical microbiology1998

Hospital specificity, region specificity, and fluconazole resistance of Candida albicans bloodstream isolates.

M A Pfaller, S R Lockhart, C Pujol, J A Swails-Wenger, S A Messer, M B Edmond, R N Jones, R P Wenzel, D R Soll

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Michael A. Pfaller, M.D.Journal of clinical microbiology · 2013
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Using C. elegans for antimicrobial drug discovery.Expert opinion on drug discovery · 2011
    Article
  11. Article
  12. Article
  13. Selective fluconazole prophylaxis in high-risk babies to reduce invasive fungal infection.Archives of disease in childhood. Fetal and neonatal edition · 2007
    Article
  14. Article
  15. Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d'Ivoire).Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M A PfallerDepartment of Pathology, University of Iowa, Iowa City 52242, USA.
S R Lockhart
C Pujol
J A Swails-Wenger
S A Messer
M B Edmond
R N Jones
R P Wenzel
D R Soll

Funding

USE OF AN IN VIVO MODEL SYSTEM TO INVESTIGATE NIDDMZ01AG000214 · NIA · NATIONAL INSTITUTE ON AGING · PI EGAN, JOSEPHINE M · 1991 to 2008
$693k
INTERDISCIPLINARY RESEARCH TRAINING PROGRAM ON AGINGT32AG000214 · NIA · UNIVERSITY OF IOWA · PI WALLACE, ROBERT BRUCE · 1991 to 2000
$164k
Intramural NIH HHS Z01 AG000214NIAID NIH HHS AI2392NIA NIH HHS T32 AG000214NIDCR NIH HHS DE1058
6 · The paper itself

Abstract

In a survey of bloodstream infection (BSI) isolates across the continental United States, 162 Candida albicans isolates were fingerprinted with the species-specific probe Ca3 and the patterns were analyzed for relatedness with a computer-assisted system. The results demonstrate that particular BSI strains are more highly concentrated in particular geographic locales and that established BSI strains are endemic in some, but not all, hospitals in the study and undergo microevolution in hospital settings. The results, however, indicate no close genetic relationship among fluconazole-resistant BSI isolates in the collection, either from the same geographic locale or the same hospital. This study represents the first of three fingerprinting studies designed to analyze the origin, genetic relatedness, and drug resistance of Candida isolates responsible for BSI.

Indexed as

Antifungal AgentsCandida albicansCandidiasisCross InfectionDNA FingerprintingDNA, FungalDrug Resistance, MicrobialFluconazoleFungemiaHospitalsHumansMicrobial Sensitivity TestsPhylogenySpecies SpecificityUnited StatesAntifungal AgentsDNA, FungalFluconazole

Identifiers

PMID9620370
PMCPMC104870

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.