ArticleProceedings of the National Academy of Sciences of the United States of America1998
Secondary absence of mitochondria in Giardia lamblia and Trichomonas vaginalis revealed by valyl-tRNA synthetase phylogeny.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 150 citations in OpenAlex.
- The history of giardiasis.Parasitology research · 2025Review
- The Evolutionary Fate of Mitochondrial Aminoacyl-tRNA Synthetases in Amitochondrial Organisms.Journal of molecular evolution · 2021Article
- The Coevolution of Plants and Microbes Underpins Sustainable Agriculture.Microorganisms · 2021Review
- Molecular basis for t6A modification in human mitochondria.Nucleic acids research · 2020Article
- Lysosomal protein trafficking in Giardia lamblia: common and distinct features.Frontiers in bioscience (Elite edition) · 2012Review
- A novel spliceosome-mediated trans-splicing can change our view on genome complexity of the divergent eukaryote Giardia intestinalis.Biophysical reviews · 2011Review
- Adaptor protein 2 regulates receptor-mediated endocytosis and cyst formation in Giardia lamblia.The Biochemical journal · 2010Article
- Prokaryotic and eukaryotic features observed on the secondary structures of Giardia SSU rRNAs and its phylogenetic implications.Parasitology research · 2007Article
- Giardia mitosomes and trichomonad hydrogenosomes share a common mode of protein targeting.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- A new scenario of plastid evolution: plastid primary endosymbiosis before the divergence of the "Plantae," emended.Journal of plant research · 2005Review
- The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions.Journal of molecular evolution · 2005Article
- Phylogenetic analysis of the complete genome sequence of Encephalitozoon cuniculi supports the fungal origin of microsporidia and reveals a high frequency of fast-evolving genes.Journal of molecular evolution · 2004Article
- Comparative analysis of the ribosomal components of the hydrogenosome-containing protist, Trichomonas vaginalis.Journal of molecular evolution · 2004Article
- Cryptosporidium parvum Cpn60 targets a relict organelle.Current genetics · 2003Article
- Complete sequence of the mitochondrial genome of Tetrahymena thermophila and comparative methods for identifying highly divergent genes.Nucleic acids research · 2003Article
- On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2003Article
- Distribution of substitution rates and location of insertion sites in the tertiary structure of ribosomal RNA.Nucleic acids research · 2001Article
- Biology of Giardia lamblia.Clinical microbiology reviews · 2001Review
- Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Aminoacyl-tRNA synthetases, the genetic code, and the evolutionary process.Microbiology and molecular biology reviews : MMBR · 2000Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Nuclear-coded valyl-tRNA synthetase (ValRS) of eukaryotes is regarded of mitochondrial origin. Complete ValRS sequences obtained by us from two amitochondriate protists, the diplomonad, Giardia lamblia and the parabasalid, Trichomonas vaginalis were of the eukaryotic type, strongly suggesting an identical history of ValRS in all eukaryotes studied so far. The findings indicate that diplomonads are secondarily amitochondriate and give further evidence for such conclusion reached recently concerning parabasalids. Together with similar findings on other amitochondriate groups (microsporidia and entamoebids), this work provides critical support for the emerging notion that no representatives of the premitochondrial stage of eukaryotic phylogenesis exist among the species living today.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.