ArticleArchives of disease in childhood1998
Prolonged mechanical ventilation as a consequence of acute illness.
Article in Archives of disease in childhood, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Article
- Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept.Frontiers in pediatrics · 2024Article
- Ventilatory support at home for children: A joint position paper from the Thoracic Society of Australia and New Zealand/Australasian Sleep Association.Respirology (Carlton, Vic.) · 2021Review
- Discharge Practices for Children with Home Mechanical Ventilation across the United States. Key-Informant Perspectives.Annals of the American Thoracic Society · 2020Article
- Noninvasive Ventilation Is Interrupted Frequently and Mostly Used at Night in the Pediatric Intensive Care Unit.Respiratory care · 2020Article
- Outcomes of children with severe bronchopulmonary dysplasia who were ventilator dependent at home.Pediatrics · 2013Article
- End-of-life discussions and advance care planning for children on long-term assisted ventilation with life-limiting conditions.Journal of palliative care · 2012Article
- Increasing prevalence of domiciliary ventilation: changes in service demand and provision in the South West of the UK.European journal of pediatrics · 2011Article
- Inpatient health care utilization for children dependent on long-term mechanical ventilation.Pediatrics · 2011Article
- Predictors of outcome for children requiring respiratory extra-corporeal life support: implications for inclusion and exclusion criteria.Intensive care medicine · 2008Article
- Sending children home on tracheostomy dependent ventilation: pitfalls and outcomes.Archives of disease in childhood · 2004Article
- Outcome of children with neuromuscular disease admitted to paediatric intensive care.Archives of disease in childhood · 2004Article
- Current status of long term ventilation of children in the United Kingdom: questionnaire survey.BMJ (Clinical research ed.) · 1999Article
- Evaluation of the Treatment of Stenotrophomonas maltophilia in Tracheostomy-Dependent Pediatric Patients.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
- How long does it take to initiate a child on long-term invasive ventilation? Results from a Canadian pediatric home ventilation program.Canadian respiratory journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine why acutely ill children become dependent upon mechanical ventilation and what happens to them.
methodsA retrospective medical record study of all patients aged between 1 month and 16 years from 1983 to 1996 who required ventilation for more than 28 days.
resultsForty children were ventilated for between 36 and 180 days before discharge or death. Before their presenting illness, 13 (33%) were normal, 15 (37%) had documented predisposing conditions such as bronchopulmonary dysplasia, and the remaining 12 (30%) had diagnoses made after admission. The cause of respiratory failure was central in four patients (10%), spinal cord in eight (20%), neuromuscular in 11 (28%), and pulmonary in 17 (42%). Severe nosocomial infection requiring treatment with intravenous antibiotics occurred in 22. To date, 16 children (40%) have died, and 10 (25%) remain ventilator dependent. Of the 24 survivors, seven (29%) have severe residual neurological deficit.
conclusionsIncreasingly, children are surviving intensive care only to remain ventilator dependent and at risk of significant comorbidity. This study should inform further debate on why such children remain ventilator dependent, and how and where they are managed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.