ArticleArchives of disease in childhood1998
Soluble thrombomodulin and antibodies to bovine glomerular endothelial cells in patients with Henoch-Schönlein purpura.
Article in Archives of disease in childhood, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Neutrophil extracellular traps-associated candidate genes in IgA vasculitis: an exploratory multi-omics analysis integrating transcriptomics and Mendelian randomization.Pediatric rheumatology online journal · 2026Article
- Clinical characteristics and risk factors analysis of abdominal symptoms in IgA vasculitis patients: a retrospective cohort study.Clinical rheumatology · 2025Article
- IgA vasculitis update: Epidemiology, pathogenesis, and biomarkers.Frontiers in immunology · 2022Review
- The role of serum myeloid-related protein 8/14 complex in Henoch-Schönlein purpura nephritis.Pediatric nephrology (Berlin, Germany) · 2012Article
- The pathogenesis and treatment of pediatric Henoch-Schönlein purpura nephritis.Clinical and experimental nephrology · 2011Review
- Systemic vasculitis in childhood.Current rheumatology reports · 2009Review
- Antiendothelial cells autoantibodies in vasculitis-associated systemic diseases.Clinical reviews in allergy & immunology · 2008Review
- Circulating IgA from acute stage of childhood Henoch-Schönlein purpura can enhance endothelial interleukin (IL)-8 production through MEK/ERK signalling pathway.Clinical and experimental immunology · 2006Article
- Pathogenic mechanisms of anti-endothelial cell antibodies (AECA): their prevalence and clinical relevance.Advances in clinical chemistry · 2006Review
- Henoch-Schönlein purpura.Current rheumatology reports · 2004Review
- Impaired vascular endothelium-dependent relaxation in Henoch-Schönlein purpura.Pediatric nephrology (Berlin, Germany) · 2004Article
- The level of IgA antibodies to human umbilical vein endothelial cells can be enhanced by TNF-alpha treatment in children with Henoch-Schönlein purpura.Clinical and experimental immunology · 2002Article
- Henoch-Schönlein purpura.Archives of disease in childhood · 1999Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the clinical significance of soluble thrombomodulin and antiendothelial cell antibodies (AECA) in children with Henoch-Schönlein purpura.
methodsBinding of serum AECA to bovine glomerular endothelial cells was evaluated by enzyme linked immunosorbent assay, cytotoxicity against glomerular endothelial cells by spectrophotometric assay, and soluble thrombomodulin concentrations by sandwich enzyme immunoassay.
resultsIgA AECA were detected in seven of 15 patients with Henoch-Schönlein purpura and nephritis, but were not detected in patients without nephritis or in controls. Patients with Henoch-Schönlein nephritis had raised titres of IgA AECA and serum thrombomodulin; severe proteinuria and renal histological changes were associated with raised titres of IgA AECA and raised serum thrombomodulin. No subjects had complement dependent cytotoxicity against glomerular endothelial cells.
conclusionsHigh titres of IgA AECA and raised serum thrombomodulin may be clinically useful markers of renal involvement in patients with Henoch-Schönlein purpura.
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