ArticleTransgenic research1998
Insect resistance of transgenic tobacco expressing an insect chitinase gene.
Article in Transgenic research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 176 citations in OpenAlex.
- Direct avirulence effector-receptor interaction confers wheat immunity against insects.Science advances · 2026Article
- Genome Sequence Analysis of NativeToxins · 2024Article
- Genome-Wide Identification and Expression Analysis ofPlants (Basel, Switzerland) · 2022Article
- Ethylene emitted by viral pathogen-infected pepper (Frontiers in plant science · 2022Article
- Comparative bioefficacy ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Rhizophagus intraradices promotes alfalfa (Medicago sativa) defense against pea aphids (Acyrthosiphon pisum) revealed by RNA-Seq analysis.Mycorrhiza · 2019Article
- Enhanced Tolerance against a Fungal Pathogen and Insect Resistance in Transgenic Tobacco Plants Overexpressing an Endochitinase Gene fromInternational journal of molecular sciences · 2019Article
- Article
- Silencing Chitinase Genes Increases Susceptibility ofBioMed research international · 2017Article
- Biochemical basis of synergism between pathogenic fungus Metarhizium anisopliae and insecticide chlorantraniliprole in Locusta migratoria (Meyen).Scientific reports · 2016Article
- Development of insect resistant maize plants expressing a chitinase gene from the cotton leaf worm, Spodoptera littoralis.Scientific reports · 2015Article
- Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination.Virology · 2015Review
- Transcriptome sequencing of transgenic poplar (Populus × euramericana 'Guariento') expressing multiple resistance genes.BMC genetics · 2014Article
- Plant defense against insect herbivores.International journal of molecular sciences · 2013Review
- Molecular cloning and functional expression of chitinase-encoding cDNA from the cabbage moth, Mamestra brassicae.Molecules and cells · 2012Article
- Article
- Article
- Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity.BMC biochemistry · 2010Article
- Insect chitinase and chitinase-like proteins.Cellular and molecular life sciences : CMLS · 2010Review
- The Chitinase A from the baculovirus AcMNPV enhances resistance to both fungi and herbivorous pests in tobacco.Transgenic research · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitinase expression in the insect gut normally occurs only during moulting, where the chitin of the peritrophic membrane is presumably degraded. Thus, insects feeding on plants that constitutively express an insect chitinase gene might be adversely affected, owing to an inappropriately timed exposure to chitinase. This hypothesis was tested by introducing a cDNA encoding a tobacco hornworm (Manduca sexta) chitinase (EC 3.2.1.14) into tobacco via Agrobacterium tumefaciens-mediated transformation. A truncated but enzymatically active chitinase was present in plants expressing the gene. Segregating progeny of high-expressing plants were compared for their ability to support growth of tobacco budworm (Heliothis virescens) larvae and for feeding damage. Both parameters were significantly reduced when budworms fed on transgenic tobacco plants expressing high levels of the chitinase gene. In contrast, hornworm larvae showed no significant growth reduction when fed on the chitinase-expressing transgenics. However, both budworm and hornworm larvae, when fed on chitinase-expressing transgenic plants coated with sublethal concentrations of a Bacillus thuringiensis toxin, were significantly stunted relative to larvae fed on toxin-treated non-transgenic controls. Foliar damage was also reduced. Plants expressing an insect chitinase gene may have agronomic potential for insect control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.