Evidence map›Paper›PMID 9605331›Full record

ArticleProtein science : a publication of the Protein Society1998

Homologues of 26S proteasome subunits are regulators of transcription and translation.

L Aravind, C P Ponting

Open access · greenAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 126 citations in OpenAlex.

  1. Article
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  4. Human eIF3: from 'blobology' to biological insight.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  5. Article
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  9. The translational factor eIF3f: the ambivalent eIF3 subunit.Cellular and molecular life sciences : CMLS · 2013
    Review
  10. Article
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  15. Article
  16. Review
  17. Article
  18. A novel type of E3 ligase for the Ufm1 conjugation system.The Journal of biological chemistry · 2010
    Article
  19. Article
  20. Inhibition of HIV-1 replication by eIF3f.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

L AravindDepartment of Biology-BSBW, Texas A&M University, College Station 77843, USA.
C P Ponting
University of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Single copies of an alpha-helical-rich motif are demonstrated to be present within subunits of the large multiprotein 26S proteasome and eukaryotic initiation factor-3 (eIF3) complexes, and within proteins involved in transcriptional regulation. In addition, p40 and p47 subunits of eIF3 are shown to be homologues of the proteasome subunit Mov34, and transcriptional regulators JAB1/pad1. Finally, the proteasome subunit S5a and the p44 subunit of the basal transcription factor IIH (TFIIH) are identified as homologues. The presence of homologous, and sometimes identical, proteins in contrasting functional contexts suggests that the large multisubunit complexes of the 26S proteasome, eIF3 and TFIIH perform overlapping cellular roles.

Indexed as

Proteasome Endopeptidase ComplexProtein BiosynthesisTranscription Factors, TFIITranscription, GeneticAmino Acid SequenceMolecular Sequence DataPeptide HydrolasesSequence AlignmentTranscription FactorsTranscription Factor TFIIHATP dependent 26S proteasePeptide HydrolasesProteasome Endopeptidase ComplexTranscription FactorsTranscription Factors, TFIITranscription Factor TFIIH

Identifiers

PMID9605331
PMCPMC2144014
OpenAlexW2062567525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.